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- Table of Contents
Facts about C-C chemokine receptor type 1.
Receptor for a C-C type chemokine.
Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level.Responsible for affecting stem cell proliferation. .
Human | |
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Gene Name: | CCR1 |
Uniprot: | P32246 |
Entrez: | 1230 |
Belongs to: |
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G-protein coupled receptor 1 family |
C-C chemokine receptor type 1; CC-CKR-1; CCR1; CCR-1; CD191 antigen; CD191; chemokine (C-C motif) receptor 1; CKR1; CKR-1; CMKBR1SCYAR1; CMKR1; HM145C-C CKR-1; LD78 receptor; Macrophage inflammatory protein 1-alpha receptor; MIP-1alpha-R; MIP1aR; RANTES receptor; RANTES-R
Mass (kDA):
41.173 kDA
Human | |
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Location: | 3p21.31 |
Sequence: | 3; NC_000003.12 (46201711..46208313, complement) |
Widely expressed in different hematopoietic cells.
Cell membrane; Multi-pass membrane protein.
PMID: 7679328 by Neote K., et al. Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor.
PMID: 7683036 by Gao J.-L., et al. Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor.
*More publications can be found for each product on its corresponding product page