C-C motif chemokine 2 Antibodies

AND CCL2 ELISA kits, C-C motif chemokine 2 Proteins

Many biological assays use antibodies to detect C-C motif chemokine 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 2 antibodies...

We validate the specificity of these antibodies to C-C motif chemokine 2 by testing them on tissues known to express CCL2 positively and negatively. Browse below to find the CCL2 antibody that suites your experiment. We have 17 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CCL2 Infographic by Boster Bio

All CCL2 Products

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Product

Figures

Specificity

Applications

Price

Anti-MCP1/CCL2 Antibody Picoband®

25 Citations 6 Q&As

Human

ELISA, IHC, WB

$370
Cat # PB9570
100 μg/vial

Human MCP-1 / CCL2 ELISA Kit PicoKine®

77 Citations 8 Q&As

Human

ELISA

$399
Cat # EK0441
96 wells/kit, with removable strips.

Mouse MCP-1 ELISA Kit PicoKine®

73 Citations 5 Q&As

Mouse

ELISA

$499
Cat # EK0568
96 wells/kit, with removable strips.

Rat MCP-1 ELISA Kit PicoKine®

43 Citations 9 Q&As

Rat

ELISA

$499
Cat # EK0902
96 wells/kit, with removable strips.

MCP-1 Monocyte Chemotactic Protein-1 Rat Recombinant Protein (CCL2)

Rat

$250
Cat # PROTP14844
2ug, 10ug, 1mg

Anti-CCL2 Antibody Picoband®

16 Citations 19 Q&As

Mouse, Rat

ELISA, WB

$370
Cat # A00056-4
100 μg/vial

Human CCL2/MCP1 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

7 Citations

Human

ELISA

$500
Cat # EZ0441
For 5 plates, 96 wells each

Mouse MCP-1 PicoKine® Quick ELISA Kit

2 Citations

Mouse

ELISA

$499
Cat # FEK0568
96 wells/kit, with removable strips.

Anti-C-C motif chemokine 2 CCL2 Antibody

5 Citations

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A00056
0.1 mg

Anti-MCP-1 CCL2 Monoclonal Antibody

Human

ELISA, WB

$380
Cat # M00056
100ul

Mouse CCL2/JE/MCP-1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP10148
Starting from 10ug

Human CCL2/MCP-1 Recombinant Protein

SDS-PAGE

$234
Cat # PROTP13500
Starting from 20ug

MCP1 (CCL2) (NM_002982) Human Over-expression Lysate

Human

$628
Cat # LS006347
100 µg

Human MCP-1 PicoKine® Quick ELISA Kit

Human

ELISA

$499
Cat # FEK0441
96 wells/kit, with removable strips.

Human recombinant CCL2 (C-C motif chemokine ligand 2) protein, AF

Human

Cell Culture

$77
Cat # PROTP13500-5
5ug,20ug,100ug

Mouse recombinant CCL2 (C-C motif chemokine ligand 2) protein, AF

Mouse

Cell Culture

$77
Cat # PROTP10148-4
5ug,20ug,100ug

Swine recombinant CCL2 (C-C Motif Chemokine Ligand 2) protein, AF

Swine

Cell Culture

$154
Cat # PROTP42831
5ug,20ug

CCL2 Overview

Facts about C-C motif chemokine 2.

CCL2 3D structure. Source: alphafold

C-C motif chemokine 2 (CCL2)

Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity.

Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Gene Information

Human
Gene Name:	CCL2
Uniprot:	P13500
Entrez:	6347

Family

Belongs to:

intercrine beta (chemokine CC) family

Alternative Names

C-C motif chemokine ligand 2; CCL2; GDCF-2; HC11; HSMCR30; MCAF; Mcp1; MCP-1; SCYA2; SMC-CF

Molecular Weight

Mass (kDA):
11.025 kDA

Genomic Context


Human

Location:	17q12
Sequence:	17; NC_000017.11 (34255285..34257203)

Tissue Specificity

Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level).

Subcellular Localizations

Secreted.

Diseases

Inflammation
Tissue Adhesions
Atherosclerosis
Inflammatory Response
Cholangiocarcinoma
Neoplasms
Fibrosis
Malignant Neoplasms
Diabetes Mellitus
Kidney Diseases
Obesity
Nervousness
Autoimmune Reaction

Sclerosis
Tumor Angiogenesis
Insulin Resistance
Arthritis
Diabetes Mellitus, Non-insulin-dependent
Pneumonia
Pathologic Neovascularization

Interacting Proteins

CCL5
CCL8
PF4
TNFAIP6

Pathways

Pathogenesis
Secretion
Inflammatory Response
Chemotaxis
Immune Response
Angiogenesis
Cell Adhesion
Chemokine Production
Cytokine Production
Cell Migration
Cell Proliferation
Cell Death
Cell Activation

Localization
Excretion
Monocyte Chemotaxis
Innate Immune Response
Hypersensitivity
Phagocytosis
Regeneration

PTMs

Phosphorylation
Cleavage
Oxidation
Reduction
Acetylation
Methylation
Biotinylation
Glycosylation
Demethylation
Nitration

Prenylation
Nitrosylation
Citrullination
Dephosphorylation
Acylation
Deacetylation
Glutathionylation
Phosphorothioation
Deamidation
Geranylgeranylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL2

References

PMID: 2923622 by Furutani Y., et al. Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF).

PMID: 2513477 by Rollins B.J., et al. The human homolog of the JE gene encodes a monocyte secretory protein.

193 Publications of Boster C-C motif chemokine 2 Antibodies & ELISA Kits

PubMed ID: PMID:31966515, Identification of genes involved in enterovirus 71 infected SK-N-SH cells
PubMed ID: PMID:31105824, Vaccarin prevents ox-LDL-induced HUVEC EndMT, inflammation and apoptosis by supp...
PubMed ID: PMID:26221302, Comparison of biomarkers in rat renal ischemia-reperfusion injury
PubMed ID: PMID:25683933, Comparative analysis of MCP-1 and TF in elderly patients with acute exacerbation...
PubMed ID: 10.7150/ijbs.25349, CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistan...
PubMed ID: 10.5551/jat.24372, Involvement of TLR4 in Oxidized LDL/β2GPI/Anti-β2GPI-Induced Transformation of...
PubMed ID: 10.4049/jimmunol.1900083, USP19 Inhibits TNF-α– and IL-1β–Triggered NF-κB Activation by Deubiquitin...
PubMed ID: 10.3892/ol.2012.1047, Endogenous PGE2 induces MCP‑1 expression via EP4/p38 MAPK signaling in melano...
PubMed ID: 10.3892/mmr.2019.10407, Tanshinone IIA attenuates cerebral aneurysm formation by inhibiting the NF‑κB...
PubMed ID: 10.3892/ijmm.2014.1844, A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-α activity
PubMed ID: 10.3892/etm.2018.6995, Thalidomide decreases high glucose‑induced extracellular matrix protein synthe...
PubMed ID: 10.3892/etm.2017.4845, Effects of leukotriene B4 on interleukin-32, interferon-γ and chemokines in rat...
PubMed ID: 10.3390/nu7085324, Apple Polyphenols Decrease Atherosclerosis and Hepatic Steatosis in ApoE−/− ...
PubMed ID: 10.3390/nu11122855, The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Infla...
PubMed ID: 10.3390/molecules190812827, Anti-Inflammatory Effect of the Blueberry Anthocyanins Malvidin-3-Glucoside and ...
PubMed ID: 10.3390/ijms21041240, Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvas...
PubMed ID: 10.3390/ijms20184389, Effect of Tff3 Deficiency and ER Stress in the Liver
PubMed ID: 10.3390/ijms19051498, Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts...
PubMed ID: 10.3390/ijms18040844, Hypaphorine Attenuates Lipopolysaccharide-Induced Endothelial Inflammation via R...
PubMed ID: 10.3389/fphar.2019.01432, The Potassium SK Channel Activator NS309 Protects Against Experimental Traumatic...
PubMed ID: 10.3389/fonc.2020.00019, Schwann Cell-Derived CCL2 Promotes the Perineural Invasion of Cervical Cancer

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page