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Cbx5 Antibodies
AND Cbx5 ELISA kits, Cbx5 Proteins
Many biological assays use antibodies to detect Cbx5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cbx5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cbx5 antibodies...
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Cbx5 Infographic by Boster Bio
All Cbx5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02780
100 μl
Cat # M02780
100 μl
Human, Mouse
ELISA
$480
Cat # EKC1723
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1723
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02780-3
100 μg/vial
Cat # A02780-3
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02780-2
100 μg/vial
Cat # M02780-2
100 μg/vial
Cbx5 Overview
Facts about Chromobox protein homolog 5.
Chromobox protein homolog 5 (Cbx5)
Component of heterochromatin that recognizes and binds histone H3 tails methylated at'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it's excluded from chromatin when'Tyr-41' of histone H3 is phosphorylated (H3Y41ph).
Can interact with lamin-B receptor (LBR). This interaction can lead to the institution of the heterochromatin with the inner nuclear membrane.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Cbx5 |
| Uniprot: | Q61686 |
| Entrez: | 12419 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Antigen p25; chromobox homolog 5 (Drosophila HP1 alpha); chromobox homolog 5 (HP1 alpha homolog, Drosophila); chromobox homolog 5; chromobox protein homolog 5; Heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HP1 alpha homolog; HP1 alpha; HP1; HP1A; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha
Molecular Weight
Mass (kDA):
22.186 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 15|15 F3 |
| Sequence: | 15; |
Diseases
- Malignant Neoplasms
- Neoplasms
- Leukemia
- Cell Invasion
- Stomach Neoplasms
- Thalassemia
- Malignant Neoplasm Of Breast
- Invasive Breast Carcinoma
- Alpha-thalassemia
- Malignant Neoplasm Of Lung
- Leukemia, Myelocytic, Acute
Pathways
- Localization
- Cell Cycle
- S Phase
- Cell Migration
- Gene Silencing
- Fertilization
- G1 Phase
- Mrna Destabilization
- Histone Modification
- Regulation Of Gene Expression
- Liver Development
- Histone Phosphorylation
PTMs
Research Areas
- Cellular Markers
- Chromatin Research
- DNA Repair
- DNA replication, Transcription, Translation and Splicing
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cbx5
bosterbio.com/bosterbio-gene-info-cards/Cbx5
References
PMID: 8978696 by le Douarin B., et al. A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.
PMID: 11107181 by Li Y.-J., et al. Contiguous arrangement of p45 NFE2, HnRNP A1, and HP1 alpha on mouse chromosome 15 and human chromosome 12: evidence for suppression of these genes due to retroviral integration within the Fli-2 locus.