This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Cysteinyl leukotriene receptor 1.
This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Human | |
---|---|
Gene Name: | CYSLTR1 |
Uniprot: | Q9Y271 |
Entrez: | 10800 |
Belongs to: |
---|
G-protein coupled receptor 1 family |
CysLT(1); CysLT1; CYSLT1CysLT1; CYSLT1R; CYSLTR; CysLTR1; Cysteinyl leukotriene D4 receptor; Cysteinyl Leukotriene R1; cysteinyl leukotriene receptor 1; Cysteinyl LeukotrieneR1; G-protein coupled receptor HG55; HG55; HMTMF81; LTD4 Receptor; MGC46139
Mass (kDA):
38.541 kDA
Human | |
---|---|
Location: | Xq21.1 |
Sequence: | X; NC_000023.11 (78271468..78327691, complement) |
Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart.
Cell membrane; Multi-pass membrane protein.
PMID: 10391245 by Lynch K.R., et al. Characterization of the human cysteinyl leukotriene CysLT1 receptor.
PMID: 10462554 by Sarau H.M., et al. Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor.
*More publications can be found for each product on its corresponding product page