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CYP39A1 Antibodies
AND CYP39A1 ELISA kits, CYP39A1 Proteins
Many biological assays use antibodies to detect CYP39A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CYP39A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CYP39A1 antibodies...
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CYP39A1 Infographic by Boster Bio
All CYP39A1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1919
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1919
1 kit, containing one 96-well plate and all necessary reagents
CYP39A1 Overview
Facts about 24-hydroxycholesterol 7-alpha-hydroxylase.
24-hydroxycholesterol 7-alpha-hydroxylase (CYP39A1)
Involved in the bile acid metabolism. Has a preference for 24-hydroxycholesterol, and converts it into a 7-alpha- hydroxylated product.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CYP39A1 |
| Uniprot: | Q9NYL5 |
| Entrez: | 51302 |
Family
| Belongs to: |
|---|
| cytochrome P450 family |
Alternative Names
Cytochrome P450 39A1; cytochrome P450, family 39, subfamily A, polypeptide 1; cytochrome P450, subfamily XXXIX (oxysterol 7 alpha-hydroxylase), polypeptide 1,24-hydroxycholesterol 7-alpha-hydroxylase; EC 1.14.13.99; hCYP39A1; Oxysterol 7-alpha-hydroxylase; oxysterol 7alpha-hydroxylase
Molecular Weight
Mass (kDA):
54.116 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p12.3 |
| Sequence: | 6; NC_000006.12 (46549580..46652849, complement) |
Tissue Specificity
Liver specific.
Subcellular Localizations
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Diseases
- Malignant Neoplasms
- Genital Neoplasms, Female
- Malignant Neoplasm Of Ovary
- Liver Diseases
- Drug-induced Liver Injury
- Malignant Neoplasm Of Breast
- Endometrial Polyp
- Cholelithiasis
- Pancreatitis
- Injury To Liver
- Alcoholic Liver Diseases
- Cardiovascular Diseases
Pathways
- Cell Proliferation
- Methylation
- Metabolic Process
- Gallstone Formation
- Dna Methylation
- Osteoblast Proliferation
- Bone Development
- Pathogenesis
- Excretion
PTMs
- Hydroxylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP39A1
bosterbio.com/bosterbio-gene-info-cards/CYP39A1
References
PMID: 10748047 by Li-Hawkins J., et al. Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol.