CXXC1 Antibodies

AND CXXC1 ELISA kits, CXXC1 Proteins

Many biological assays use antibodies to detect CXXC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CXXC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CXXC1 antibodies...

We validate the specificity of these antibodies to CXXC1 by testing them on tissues known to express CXXC1 positively and negatively. Browse below to find the CXXC1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CXXC1 Infographic by Boster Bio

All CXXC1 Products

Product

Figures

Specificity

Applications

Price

Anti-CXXC1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A05025
100ul

CGBP (CXXC1) (NM_014593) Human Over-expression Lysate

Human

$628
Cat # LS030827
100 µg

CXXC1 Overview

Facts about CXXC-type zinc finger protein 1.

CXXC1 3D structure. Source: alphafold

CXXC-type zinc finger protein 1 (CXXC1)

Transcriptional activator that exhibits a special DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. .

Gene Information

Human
Gene Name:	CXXC1
Uniprot:	Q9P0U4
Entrez:	30827

Family

Belongs to:

No superfamily

Alternative Names

CFP1CXXC-type zinc finger protein 1; CGBPPHD finger and CXXC domain-containing protein 1; CpG binding protein; cpG-binding protein; CXXC finger 1 (PHD domain); CXXC finger protein 1; DNA-binding protein with PHD finger and CXXC domain; hCGBP; HsT2645; PCCX12410002I16Rik; PHF185830420C16Rik; SPP1; ZCGPC1; zinc finger, CpG binding-type containing 1

Molecular Weight

Mass (kDA):
75.712 kDA

Genomic Context


Human

Location:	18q21.1
Sequence:	18; NC_000018.10 (50282343..50288322, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus speckle. Nucleus. Associated with euchromatin. During mitosis, excluded from condensed chromosomes.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Neoplasms
Mammary Neoplasms
Infective Disorder
Leukemia
Metabolic Bone Disorder
Autoimmunity
Adenoma
Tetanus
Colonic Neoplasms
Malignant Tumor Of Colon
Neoplasm Invasiveness

Carcinoma
Carcinogenesis
Neoplasm/cancer Invasiveness
Colorectal Cancer
Sporadic Breast Carcinoma
Bacterial Infections
Purpura, Thrombocytopenic, Idiopathic

Interacting Proteins

MEOX2
RBBP5
TAX1BP1
TP53

Pathways

Methylation
Dna Methylation
Histone Methylation
Histone Modification
Cell Activation
Aging
Dna Repair
Proteolysis
Hypersensitivity
Respiratory Burst
B Cell Activation
Spermatogenesis

Demethylation
Translation
S Phase
Regulation Of Translation
Chromatin Modification
Pathogenesis
Secretion

PTMs

Methylation
Demethylation

Phosphorylation
Reduction

Cleavage

Research Areas

Neuroscience
Unfolded Protein Response (UPR)

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CXXC1

References

PMID: 10688657 by Voo K.S., et al. Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1.

PMID: 10799292 by Fujino T., et al. PCCX1, a novel DNA-binding protein with PHD finger and CXXC domain, is regulated by proteolysis.