Interleukin-8 (CXCL8)

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. Additionally it is involved in neutrophil activation.

It's released from several cell types in response to an inflammatory stimulus. IL-8(6-77) includes a 5-10-fold higher action on neutrophil activation, IL-8(5-77) has increased action on neutrophil activation and IL-8(7-77) has a greater affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.