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- Table of Contents
4 Citations 9 Q&As
1 Citations 5 Q&As
Facts about C-X-C motif chemokine 3.
May play a role in inflammation and apply its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
Human | |
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Gene Name: | CXCL3 |
Uniprot: | P19876 |
Entrez: | 2921 |
Belongs to: |
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intercrine alpha (chemokine CxC) family |
chemokine (C-X-C motif) ligand 3; CINC-2; CINC-2b; C-X-C motif chemokine 3; CXCL3; Dcip1; Gm1960; GRO gamma; GRO3 oncogene; GRO3; GROG; GRO-gamma; GRO-gamma(1-73); Growth-regulated protein gamma; Macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; MGSA gamma; MIP2B; MIP-2b; MIP2-beta; SCYB3
Mass (kDA):
11.342 kDA
Human | |
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Location: | 4q13.3 |
Sequence: | 4; NC_000004.12 (74036589..74038689, complement) |
Secreted.
PMID: 2201751 by Tekamp-Olson P., et al. Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues.
PMID: 2217207 by Haskill S., et al. Identification of three related human GRO genes encoding cytokine functions.
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