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- Table of Contents
2 Citations 7 Q&As
1 Citations 11 Q&As
Facts about C-X-C motif chemokine 13.
Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils.
Doesn't induce calcium release in B- lymphocytes.Binds to BLR1/CXCR5. .
Human | |
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Gene Name: | CXCL13 |
Uniprot: | O43927 |
Entrez: | 10563 |
Belongs to: |
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intercrine alpha (chemokine CxC) family |
ANGIE; ANGIE2; B cell-attracting chemokine 1; B lymphocyte chemoattractant; BCA1; BCA-1; BCA1B-cell chemoattractant; BCA-1CXC chemokine BLC; B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1); BLC; BLCSmall-inducible cytokine B13; BLR1L; B-lymphocyte chemoattractant; chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant); chemokine (C-X-C motif) ligand 13; C-X-C motif chemokine 13; CXCL13; SCYB13; SCYB13B-cell-attracting chemokine 1; small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cellchemoattractant)
Mass (kDA):
12.664 kDA
Human | |
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Location: | 4q21.1 |
Sequence: | 4; NC_000004.12 (77511753..77611834) |
Highest levels in liver, followed by spleen, lymph node, appendix and stomach. Low levels in salivary gland, mammary gland and fetal spleen.
Secreted.
PMID: 9486651 by Gunn M.D., et al. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1.
PMID: 9463416 by Legler D.F., et al. B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5.
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