Cystatin-S Antibodies

AND CST4 ELISA kits, Cystatin-S Proteins

Many biological assays use antibodies to detect Cystatin-S, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cystatin-S in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cystatin-S antibodies...

We validate the specificity of these antibodies to Cystatin-S by testing them on tissues known to express CST4 positively and negatively. Browse below to find the CST4 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CST4 Infographic by Boster Bio

All CST4 Products

Product

Figures

Specificity

Applications

Price

Anti-CYTS CST4 Antibody

Human

ELISA, WB

$380
Cat # A07438
100ul

Cystatin S (CST4) (NM_001899) Human Recombinant Protein

$1249
Cat # PROTP01036
20 µg

Anti-Cystatin S (CST4) Mouse Monoclonal Antibody [Clone ID: OTI2H10]

Human

Flow Cytometry, IF, WB

$523
Cat # M07438
100 µl

Cystatin S (CST4) (NM_001899) Human Over-expression Lysate

Human

$628
Cat # LS001472
100 µg

CST4 Overview

Facts about Cystatin-S.

CST4 3D structure. Source: alphafold

Cystatin-S (CST4)

This protein strongly inhibits papain and ficin, partly inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.

Gene Information

Human
Gene Name:	CST4
Uniprot:	P01036
Entrez:	1472

Family

Belongs to:

cystatin family

Alternative Names

CST4; cystatin 4; Cystatin S; Cystatin-4; cystatin-S; cystatin-SA-III; MGC71923; Salivary acidic protein 1

Molecular Weight

Mass (kDA):
16.214 kDA

Genomic Context


Human

Location:	20p11.21
Sequence:	20; NC_000020.11 (23685640..23689025, complement)

Tissue Specificity

Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid.

Subcellular Localizations

Secreted.

Diseases

Salivary Gland Diseases
Periodontitis
Sjogren's Syndrome
Neoplasms
Nervousness
Infective Disorder
Instabilities, Chromosomal
Neoplasm Metastasis
Communicable Diseases
Aneuploidy
Malignant Neoplasms
Metastatic Malignant Neoplasm To The Bone
Barrett's Adenocarcinoma

Barrett Esophagus
Rheumatoid Arthritis
Esophageal Adenocarcinoma
Esophageal Neoplasms
Stress, Psychological
Adenocarcinoma
Sialadenitis

Pathways

Secretion
Dna Replication
Cell Cycle
Innervation
Chromosome Segregation

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CST4

References

PMID: 1898352 by Bobek L.A., et al. Human salivary cystatin S. Cloning, sequence analysis, hybridization in situ and immunocytochemistry.

PMID: 1334620 by Saitoh E., et al. Characterization of two members (CST4 and CST5) of the cystatin gene family and molecular evolution of cystatin genes.