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- Table of Contents
Facts about Granulocyte colony-stimulating factor receptor.
Moreover it can function in some adhesion or recognition events at the cell surface. .
Human | |
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Gene Name: | CSF3R |
Uniprot: | Q99062 |
Entrez: | 1441 |
Belongs to: |
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type I cytokine receptor family |
CD114 antigen; CD114; colony stimulating factor 3 receptor (granulocyte); CSF3R; Csfgr; G-CSF R; G-CSF receptor; GCSFR; G-CSFR; GCSFRG-CSF-R; granulocyte colony-stimulating factor receptor
Mass (kDA):
92.156 kDA
Human | |
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Location: | 1p34.3 |
Sequence: | 1; NC_000001.11 (36466043..36483314, complement) |
One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta.
[Isoform 2]: Secreted.; Cell membrane; Single-pass type I membrane protein.
PMID: 2147944 by Larsen A., et al. Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.
PMID: 1701053 by Fukunaga R., et al. Three different mRNAs encoding human granulocyte colony-stimulating factor receptor.