Alpha-crystallin A chain Antibodies

AND CRYAA ELISA kits, Alpha-crystallin A chain Proteins

Many biological assays use antibodies to detect Alpha-crystallin A chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alpha-crystallin A chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alpha-crystallin A chain antibodies...

We validate the specificity of these antibodies to Alpha-crystallin A chain by testing them on tissues known to express CRYAA positively and negatively. Browse below to find the CRYAA antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CDH12 Next: CRYBA2

CRYAA Infographic by Boster Bio

All CRYAA Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Alpha A Crystallin/CRYAA Antibody Picoband®

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IHC, IHC-F, ICC, WB

$370
Cat # PB9940
100 μg/vial

Anti-Alpha A Crystallin Monoclonal Antibody

4 Q&As

Bovine, Human, Mouse, Rat

ELISA, IF, ICC, WB

$380
Cat # M01900
200ug

Anti-Alpha-crystallin A chain CRYAA Antibody

Human, Mouse, Rat, Zebrafish

IF, ICC, WB

$405
Cat # A01900
100ul

alpha A Crystallin (CRYAA) (NM_000394) Human Recombinant Protein

$1062
Cat # PROTP02489
20 µg

Anti-alpha A Crystallin (CRYAA) Mouse Monoclonal Antibody [Clone ID: OTI3B12]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M01900-1
100 µl

Anti-Alpha A Crystallin Antibody Picoband® (monoclonal, 10B9)

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M01900-2
100 μg/vial

Anti-Alpha A Crystallin Antibody Picoband® (monoclonal, 8H6)

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # M01900-3
100 μg/vial

Anti-CRYAA Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M01900-4
100 μl/vial

CRYAA Overview

Facts about Alpha-crystallin A chain.

CRYAA 3D structure. Source: alphafold

Alpha-crystallin A chain (CRYAA)

Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of different proteins under a broad range of stress conditions.

Gene Information

Human
Gene Name:	CRYAA
Uniprot:	P02489
Entrez:	1409

Family

Belongs to:

small heat shock protein (HSP20) family

Alternative Names

AlphaA Crystallin; CRYA1; CRYA1crystallin, alpha-1; CRYAA; crystallin, alpha A; Heat shock protein beta-4; HSPB4; HSPB4alpha-crystallin A chain; human alphaA-crystallin (CRYA1), 10HspB4

Molecular Weight

Mass (kDA):
19.909 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (43169008..43172810)

Tissue Specificity

Expressed in eye lens.

Subcellular Localizations

Cytoplasm. Nucleus. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.

Diseases

Cataract
Corneal Diseases
Nuclear Cataract
Eye Abnormalities
Blind Vision
Disorder Of Eye
Senile Cataract
Lens Diseases
Visual Impairment
Congenital Lamellar Cataract
Congenital Coloboma Of Iris

Retinoblastoma
Microphthalmos
Eye Diseases, Hereditary
Lens Opacities
Retinal Diseases
Congenital Ocular Coloboma (disorder)

Interacting Proteins

CRYAB
CRYGC
GORASP2
SDCBP
SPG21

WDYHV1

Pathways

Pathogenesis
Localization
Cell Differentiation
Eye Development
Oncogenesis
Cell Death
Angiogenesis
Cell Adhesion
Transport
Cell Migration
Aging
Neurogenesis
Virulence

Cell Cycle Arrest
Gene Conversion
Reverse Transcription
Cell Cycle
Protein Refolding
Cell Proliferation
Dna Methylation

PTMs

Phosphorylation
Demethylation

Methylation
Deamidation

Research Areas

Membrane Trafficking and Chaperones
Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CRYAA

References

PMID: 817940 by de Jong W.W., et al. The amino acid sequence of the A chain of human alpha-crystallin.

PMID: 8587135 by Jaworski C.J.; A reassessment of mammalian alpha A-crystallin sequences using DNA sequencing: implications for anthropoid affinities of tarsier.