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- Table of Contents
Facts about Cryptochrome-1.
It's derived from the Latin roots'circa' (about) and'diem' (day) and acts as an important regulator of a wide variety of physiological functions such as metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two significant components: the central clock, living in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks which are found in virtually every tissue and organ system.
Human | |
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Gene Name: | CRY1 |
Uniprot: | Q16526 |
Entrez: | 1407 |
Belongs to: |
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DNA photolyase class-1 family |
CRY1; cryptochrome 1 (photolyase-like); Cryptochrome I; PHLL1; PHLL1cryptochrome-1; photolyase-like cryptochrome 1
Mass (kDA):
66.395 kDA
Human | |
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Location: | 12q23.3 |
Sequence: | 12; NC_000012.12 (106991364..107093872, complement) |
Cytoplasm. Nucleus. Translocated to the nucleus through interaction with other clock proteins such as PER2 or ARNTL/BMAL1.
PMID: 8909283 by Hsu D.S., et al. Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.
PMID: 8921389 by van der Spek P.J., et al. Cloning, tissue expression, and mapping of a human photolyase homolog with similarity to plant blue-light receptors.