CREB3 Antibodies

AND CREB3 ELISA kits, CREB3 Proteins

Many biological assays use antibodies to detect CREB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CREB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CREB3 antibodies...

We validate the specificity of these antibodies to CREB3 by testing them on tissues known to express CREB3 positively and negatively. Browse below to find the CREB3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CREB3 Infographic by Boster Bio

All CREB3 Products

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Anti-CREB3 Antibody

3 Q&As

Human, Mouse, Rat

ELISA, WB

$399
Cat # A03564-1
100μl

CREB3 (NM_006368) Human Over-expression Lysate

Human

$628
Cat # LS010488
100 µg

CREB3 Overview

Facts about Cyclic AMP-responsive element-binding protein 3.

CREB3 3D structure. Source: alphafold

Cyclic AMP-responsive element-binding protein 3 (CREB3)

Endoplasmic reticulum (ER)-bound sequence-specific transcription factor that directly binds DNA and activates transcription (PubMed:9271389, PubMed:19779205, PubMed:10984507, PubMed:15845366, PubMed:16940180). Plays a role in the unfolded protein response (UPR), promoting cell survival versus ER stress- induced apoptotic cell death (PubMed:15845366, PubMed:16940180).

Also involved in cell proliferation, migration and differentiation, tumor suppression and inflammatory gene expression. Acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration (PubMed:19779205, PubMed:15001559, PubMed:17296613).

Gene Information

Human
Gene Name:	CREB3
Uniprot:	O43889
Entrez:	10488

Family

Belongs to:

bZIP family

Alternative Names

basic leucine zipper protein; cAMP responsive element binding protein 3 (luman); cAMP responsive element binding protein 3; cAMP-responsive element-binding protein 3; CREB-3; cyclic AMP response element (CRE)-binding protein/activating transcriptionfactor 1; cyclic AMP-responsive element-binding protein 3; LUMAN; LZIPMGC15333; MGC19782; Transcription factor LZIP-alpha

Molecular Weight

Mass (kDA):
41.379 kDA

Genomic Context


Human

Location:	9p13.3
Sequence:	9; NC_000009.12 (35732666..35736999)

Tissue Specificity

Ubiquitously expressed (PubMed:9271389, PubMed:19779205). Expressed in dendritic cells (DC). Weakly expressed in monocytes (at protein level) (PubMed:20546900).

Subcellular Localizations

[Isoform 1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus. Colocalizes with HCFC1 in neuronal cell bodies of the trigeminal ganglia (PubMed:10623756). Colocalizes with DCSTAMP in the ER membrane of immature dendritic cell (DC) (PubMed:20546900). Colocalizes with CANX, CCR1, HCFC1 in the ER membrane (PubMed:10623756).; [Isoform 2]: Nucleus. Cytoplasm. Predominantly in the nucleus (PubMed:19779205). Not associated with membranes (PubMed:19779205).; [Processed cyclic AMP-responsive element-binding protein 3]: Nucleus. Upon RIP activation the transcriptiona