CPSF4 Antibodies

AND CPSF4 ELISA kits, CPSF4 Proteins

Many biological assays use antibodies to detect CPSF4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CPSF4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CPSF4 antibodies...

We validate the specificity of these antibodies to CPSF4 by testing them on tissues known to express CPSF4 positively and negatively. Browse below to find the CPSF4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CPSF4 Infographic by Boster Bio

All CPSF4 Products

Product

Figures

Specificity

Applications

Price

Human CPSF4 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTO95639
Starting from 20ug

CPSF30 (CPSF4) (NM_006693) Human Over-expression Lysate

Human

$628
Cat # LS010898
100 µg

CPSF4 Overview

Facts about Cleavage and polyadenylation specificity factor subunit 4.

CPSF4 3D structure. Source: alphafold

Cleavage and polyadenylation specificity factor subunit 4 (CPSF4)

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).

Gene Information

Human
Gene Name:	CPSF4
Uniprot:	O95639
Entrez:	10898

Family

Belongs to:

CPSF4/YTH1 family

Alternative Names

30kD; cleavage and polyadenylation specific factor 4, 30kD subunit; cleavage and polyadenylation specific factor 4, 30kDa; CPSF 30 kDa subunit; neb-1; No arches homolog; no arches-like zinc finger protein; NS1 effector domain-binding protein 1

Molecular Weight

Mass (kDA):
30.255 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (99438912..99457377)

Subcellular Localizations

Nucleus.

Interacting Proteins

CDC73
MEOX2

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CPSF4

References

PMID: 9224719 by Barabino S.M.L., et al. The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins.

PMID: 9651582 by Nemeroff M.E., et al. Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs.