CPN1 Antibodies

Carboxypeptidase N catalytic chain (CPN1)

Protects the body from powerful vasoactive and inflammatory peptides comprising C-terminal Arg or Lys (such as kinins or anaphylatoxins) that are released into the circulation. .

Gene Information

Human
Gene Name:	CPN1
Uniprot:	P15169
Entrez:	1369

Family

Belongs to:
peptidase M14 family

Alternative Names

ACBP; Anaphylatoxin inactivator; Arginine carboxypeptidase; carboxypeptidase N polypeptide 1 50 kD; Carboxypeptidase N polypeptide 1; Carboxypeptidase N small subunit; carboxypeptidase N, polypeptide 1; carboxypeptidase N, polypeptide 1, 50kD; CPNcarboxypeptidase N catalytic chain; EC 3.4.17; EC 3.4.17.3; FLJ40792; kininase I; kininase-1; Lysine carboxypeptidase; Plasma carboxypeptidase B; SCPNcarboxypeptidase N catalytic subunit; Serum carboxypeptidase N

Molecular Weight

Mass (kDA):
52.286 kDA

Genomic Context

Human
Location:	10q24.2
Sequence:	10; NC_000010.11 (100042193..100081869, complement)

Tissue Specificity

Synthesized in the liver and secreted in plasma.

Subcellular Localizations

Secreted, extracellular space.

Diseases

• Plant Diseases
• Inflammation
• Anaphylaxis
• Leukoencephalopathy, Progressive Multifocal
• Coughing
• Inflammatory Bowel Diseases
• Ulcerative Colitis
• Ulcer
• Coinfection
• Hypertensive Disease
• Encephalopathies
• Dwarfism
• Kidney Diseases

• Allergy
• Crohn Disease
• Anaphylotoxin Inactivator Deficiency
• Tissue Damage
• Von Willebrand Disease
• Colitis
• Persistent Cough

Pathways

• Disease Resistance
• Cell Death
• Defense Response
• Localization
• Regulation Of Cell Death
• Complement Activation
• Hypersensitivity
• Protein Secretion
• Tropism

• Lipid Modification
• Cell Growth
• Pathogenesis
• Secretion

PTMs

• Cleavage

• Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CPN1

Boster Bio - Best Uses Of The CPN1 Marker

This article will discuss the Boster Bio Anti-CPN Cat CPN1 Marker as well as the research primary, secondary antibodies and PICOKINE (tm) ELISA kit. This information will be helpful to any scientist doing research in a specific species. All scientists around world can use the information contained herein. For more information, visit Boster Bio.

Boster Bio Anti-CPN cat CPN1 Marker

Boster Bio Anti-CPN Cat CPM1 Marker has an anti-human antibody reaction. The antibody can be stored in liquid in PBS for up to a year. There are many prices for blocking peptides depending on the length and price. Boster offers both liquid and ELISA kits that use this antibody for specific applications.

Boster Bio's research primary antibodies and secondary antibody products

Boster Bio has ELISA kits for detecting cluster differentiation antigens. The antibodies are capable of detecting biomarkers in the fields of cancer, developmental biology, neurosciences, inflammation, and immune system function. The primary antibodies have a high level of specificity, with picogram-level sensitivities. Boster Bio research antibodies are available through tebubio.

Primary antibodies recognize a specific peptide that has an immunodominant pattern. This is a region in which a protein is likely to provoke an immunological response in a laboratory environment. The peptide is composed of a series of hydrophilic and hydrophobic amino acid residues. The antibodies bind to the peptide in a column with 0.1 M glycine-HCl buffer, pH 2.5-8.0.

These secondary and primary antibodies were derived from tissue taken from knockout mice. They are highly specific against CPN1 markers. They are designed to recognize an antigen specific epitope and show their binding specificity under the exact same conditions as fixed cells. They also show that primary antigens do not bind to unbound antigens in cells that have been fixated and treated with detergent.

To verify the validity of immunohistochemistry, it is important that isotypespecific immunoglobulins are used in addition to the primary antibodies. These serum should be used to control any immunohistochemical experiments. It is essential to include both a positive and a negatively controlled control. Both positive as well as negative controls should be performed using preimmune and isotype-specific sera. In the event of insufficient results, the positive control should not contain primary antibody.

Boster Bio's research ELISA Kits

An ELISA kit can detect many proteins, including the CPN1 marker. These kits can be used to study the expression of specific proteins in different tissues, as well as the interaction between different enzymes and substrates. They are perfect for biomarkers, including in the areas of developmental biology and neurosciences, inflammation, cancer, and cancer. Boster Bio's CPN1 marker research ELISA kits are highly sensitive and can be used for monitoring biomarkers down to a picogram level. Through its website, Tebu-bio, the company provides immunological kits and reagents.

Boster Bio has developed the PICOKINE(tm), an ELISA kit.

The new PICOKINETM sensitivity ELISA kits (CPN1 gene) are designed for enhancing the sensitivity of the ELISA up to single picogram levels. Picokine(tm), a technology that maximizes the binding effectiveness of capture antibodies, is available. This results in a ELISA kit with high sensitivity but low background. It can be used for a wide variety samples and has enough reagents to run up to 96 tests. The kits can be purchased from Tebu-bio or Boster Bio.

Boster Bio provides ELISA kits against the CPN1 gene. Boster Bio also offers a variety custom services to meet the needs of researchers. Their labs were the first European Raybiotech laboratories. They offer ELISA kits for PICOKINE(tm), as well as thematic newsletters and other services.