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- Table of Contents
Facts about Cytochrome c oxidase assembly protein COX15 homolog.
Human | |
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Gene Name: | COX15 |
Uniprot: | Q7KZN9 |
Entrez: | 1355 |
Belongs to: |
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COX15/CtaA family |
COX15 (yeast) homolog, cytochrome c oxidase assembly protein; COX15 homolog, cytochrome c oxidase assembly protein (yeast); cytochrome c oxidase assembly protein COX15 homolog; cytochrome c oxidase subunit 15; EC 1.4.4.2; EC 3.1.3.5
Mass (kDA):
46.03 kDA
Human | |
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Location: | 10q24.2 |
Sequence: | 10; NC_000010.11 (99694293..99732131, complement) |
Predominantly found in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle, heart, and brain.
Mitochondrion membrane; Multi-pass membrane protein.
PMID: 9878253 by Petruzzella V., et al. Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain.
PMID: 12474143 by Antonicka H., et al. Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy.