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Cortistatin Antibodies

AND CORT ELISA kits, Cortistatin Proteins

Many biological assays use antibodies to detect Cortistatin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cortistatin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cortistatin antibodies...

We validate the specificity of these antibodies to Cortistatin by testing them on tissues known to express CORT positively and negatively. Browse below to find the CORT antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CORT Infographic by Boster Bio

CORT protein infographic

All CORT Products

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Cortistatin (CORT) (NM_001302) Human Over-expression Lysate

Human

$628
Cat # LS001325
100 µg

CORT Overview

Facts about Cortistatin.

CORT 3D structure

CORT 3D structure. Source: alphafold

Cortistatin (CORT)

Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by forskolin through SSTRs.

.

Gene Information

Human
Gene Name:	CORT
Uniprot:	O00230
Entrez:	1325

Gene Information

Family

Belongs to:

somatostatin family

Family

Alternative Names

cortistatin; cortistatin-14; cortistatin-17; cortistatin-29; CST-14; CST-17; CST-29; MGC32686; preprocortistatin

Molecular Weight

Mass (kDA):
11.532 kDA

Molecular Weight

Genomic Context


Human

Location:	1p36.22
Sequence:	1; NC_000001.11 (10450031..10451998)

Tissue Specificity

Expressed in a subset of GABAergic cells in the cortex and hippocampus.

Subcellular Localizations

Secreted.

Subcellular Localization

Diseases

Stress, Psychological
Physiological Stress
Depressive Disorder
Pituitary Diseases
Anxiety Disorders
Nervousness
Inflammation
Impairment (finding)
Malnutrition
Major Depressive Disorder
Pain

Paroxysmal Nocturnal Dyspnea
Mood Disorders
Neoplasms
Memory Impairment
Nerve Degeneration
Post-traumatic Stress Disorder

Disease

Interacting Proteins

APP

Interacting Proteins

Pathways

Secretion
Response To Stress
Sensitization
Aging
Cell Proliferation
Localization
Swimming
Habituation
Neurogenesis
Corticosterone Secretion
Circadian Rhythm
Immune Response

Cognition
Transport
Locomotion
Hypersensitivity
Glucocorticoid Secretion
Pathogenesis
Reflex

Pathways

PTMs

Phosphorylation
Nitration
Oxidation
Cleavage

Reduction
Methylation
Deamination
Acetylation

Iodination

Research Areas

Cytokine Research

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CORT

References

PMID: 9125122 by Fukusumi S., et al. Identification and characterization of a novel human cortistatin-like peptide.

PMID: 9205124 by de Lecea L., et al. Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin.