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- Table of Contents
Facts about Coatomer subunit gamma-2.
In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). .
Human | |
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Gene Name: | COPG2 |
Uniprot: | Q9UBF2 |
Entrez: | 26958 |
Belongs to: |
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COPG family |
Coatomer subunit gamma-2
Mass (kDA):
97.622 kDA
Human | |
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Location: | 7q32.2 |
Sequence: | 7; NC_000007.14 (130506238..130668758, complement) |
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Tends to be more abundant in the trans-Golgi network compared to the cis-Golgi.
PMID: 10556286 by Blagitko N., et al. Gamma2-COP, a novel imprinted gene on chromosome 7q32, defines a new imprinting cluster in the human genome.
PMID: 11056392 by Futatsumori M., et al. Identification and characterization of novel isoforms of COP I subunits.