COL7A1 Antibodies

AND COL7A1 ELISA kits, COL7A1 Proteins

Many biological assays use antibodies to detect COL7A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COL7A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COL7A1 antibodies...

We validate the specificity of these antibodies to COL7A1 by testing them on tissues known to express COL7A1 positively and negatively. Browse below to find the COL7A1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COL7A1 Infographic by Boster Bio

All COL7A1 Products

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Anti-Collagen alpha-1(VII) chain COL7A1 Antibody

Human, Mouse

ELISA, IF, IHC

$380
Cat # A01170
100ul

Anti-Collagen VII/COL7A1 Antibody Picoband®

2 Citations 1 Q&As

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A01170-1
100 μg/vial

COL7A1 Overview

Facts about Collagen alpha-1(VII) chain.

Collagen alpha-1(VII) chain (COL7A1)

Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. .

Gene Information

Human
Gene Name:	COL7A1
Uniprot:	Q02388
Entrez:	1294

Family

Belongs to:

No superfamily

Alternative Names

Collagen 7; collagen alpha-1(VII) chain; collagen VII, alpha-1 polypeptide; collagen, type VII, alpha 1; Collagen-7; EBD1; EBDCT; EBR1; epidermolysis bullosa, dystrophic, dominant and recessive; LC collagen; long chain collagen; Long-chain collagen

Molecular Weight

Mass (kDA):
295.22 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (48564073..48595329, complement)

Subcellular Localizations

Secreted, extracellular space, extracellular matrix, basement membrane.

Diseases

Epidermolysis Bullosa
Epidermolysis Bullosa Dystrophica
Hallopeau-siemens Disease
Bulla
Dermatologic Disorders
Cockayne-touraine Disease
Cicatrix
Skin Diseases, Genetic
Tissue Adhesions
Pruritus
Dystrophy
Mucinous Adenocarcinoma

Dystrophia Unguium
Hereditary Diseases
Carcinoma
Malignant Squamous Cell Neoplasm
Prurigo
De Novo Mutation

Interacting Proteins

MIA3

Pathways

Pathogenesis
Secretion
Translation
Localization
Wound Healing
Cell Adhesion
Cell Growth
Keratinization
Response To Wounding
Immune Response
Complement Activation
Inflammatory Response
Sensitization

Mrna Splicing
Heteroduplex Formation
Embryo Implantation
Cell Differentiation
Mating
Bioluminescence
Cell Proliferation

PTMs

Cleavage

Research Areas

Cell Biology
Cellular Markers
Extracellular Matrix

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL7A1

References

PMID: 8088784 by Christiano A.M., et al. Structural organization of the human type VII collagen gene (COL7A1), composed of more exons than any previously characterized gene.

PMID: 8051117 by Christiano A.M., et al. Cloning of human type VII collagen. Complete primary sequence of the alpha 1(VII) chain and identification of intragenic polymorphisms.

2 Publications of Boster COL7A1 Antibodies & ELISA Kits

PubMed ID: 10.1038/s41401-021-00782-6, CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice vi...
PubMed ID: 10.1016/j.biomaterials.2021.121260, An improved osseointegration of metal implants by pitavastatin loaded multilayer...

*More publications can be found for each product on its corresponding product page