Collagen alpha-1(I) chain Antibodies

AND COL1A1 ELISA kits, Collagen alpha-1(I) chain Proteins

Many biological assays use antibodies to detect Collagen alpha-1(I) chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Collagen alpha-1(I) chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Collagen alpha-1(I) chain antibodies...

We validate the specificity of these antibodies to Collagen alpha-1(I) chain by testing them on tissues known to express COL1A1 positively and negatively. Browse below to find the COL1A1 antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COL1A1 Video by Boster Bio

All COL1A1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Collagen I/COL1A1 Antibody Picoband®

50 Citations 15 Q&As

Human

IF, IHC, WB

$370
Cat # PB9938
100 μg/vial

Anti-Collagen I/COL1A1 Antibody Picoband®

59 Citations 17 Q&As

Mouse, Rat

IHC, WB

$370
Cat # PB9939
100 μg/vial

Anti-Collagen I/COL1A1 Antibody Picoband®

56 Citations

Human, Mouse

IHC, WB

$370
Cat # PA2140-1
100 μg/vial

Anti-Collagen I/COL1A1 Antibody Picoband®

96 Citations 20 Q&As

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # PA2140-2
100 μg/vial

Anti-COLLAGEN Type I COL1A1 Antibody Biotin Conjugated

33 Citations 16 Q&As

Human, Mouse, Rat

Dot blot, Flow Cytometry

$658
Cat # B00329
100ug

Anti-Collagen I COL1A1 Rabbit Monoclonal Antibody

1 Q&As

Human

IHC, WB

$370
Cat # M00624
100 μl

Human Pro-collagen Iα1/COL1A1 ELISA Kit PicoKine®

8 Citations 8 Q&As

Human

ELISA

$450
Cat # EK1692
96 wells/kit, with removable strips.

Anti-Collagen I COL1A1 Monoclonal Antibody

6 Citations

Human, Mouse, Rat

IF, IHC-P, ICC

$380
Cat # M00329-1
100ul

COL1A1 Overview

Facts about Collagen alpha-1(I) chain.

COL1A1 3D structure. Source: alphafold

Collagen alpha-1(I) chain (COL1A1)

Type I collagen is a member of group I collagen (fibrillar forming collagen). .

Gene Information

Human
Gene Name:	COL1A1
Uniprot:	P02452
Entrez:	1277

Family

Belongs to:

fibrillar collagen family

Alternative Names

Alpha-1 type I collagen; COL1A1; Collagen 1 alpha 1; Collagen 1; collagen alpha 1 chain type I; collagen alpha-1(I) chain; Collagen I alpha 1; collagen of skin, tendon and bone, alpha-1 chain; collagen, type I, alpha 1; Collagen1; Collagen-1; OI4; pro-alpha-1 collagen type 1

Molecular Weight

Mass (kDA):
138.941 kDA

Genomic Context


Human

Location:	17q21.33
Sequence:	17; NC_000017.11 (50184096..50201649, complement)

Tissue Specificity

Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Osteogenesis Imperfecta
Fibrosis
Fracture
Neoplasms
Osteoporosis
Dermatofibrosarcoma
Dermatofibrosarcoma Protuberans
Skin Neoplasms
Osteopenia
Malignant Neoplasms
Connective Tissue Diseases
Hypertrophy
Inflammation

Ehlers-danlos Syndrome
Sclerosis
Tissue Adhesions
Neoplasm Metastasis
Diffuse Scleroderma
Bone Diseases
Chromosomal Translocation

Interacting Proteins

Pathways

Pathogenesis
Osteoblast Differentiation
Cell Proliferation
Secretion
Regeneration
Wound Healing
Dentinogenesis
Cell Growth
Aging
Ossification
Translation
Bone Resorption
Reverse Transcription

Angiogenesis
Localization
Bone Development
Bone Remodeling
Methylation
Cell Differentiation
Dna Methylation

PTMs

Cleavage
Phosphorylation
Methylation
Hydroxylation
Demethylation
Phosphorothioation
Sulphation
Carboxylation

Deamination
Deacetylation
Nitrosylation
Ubiquitination
Nitration
Reduction
Glycosylation
Acetylation

Oxidation

Research Areas

Cell Biology
Cellular Markers
Extracellular Matrix
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL1A1

References

PMID: 2843432 by D'Alessio M., et al. Complete nucleotide sequence of the region encompassing the first twenty-five exons of the human pro alpha 1(I) collagen gene (COL1A1).

PMID: 3178743 by Tromp G., et al. Structure of a full-length cDNA clone for the prepro alpha 1(I) chain of human type I procollagen.

121 Publications of Boster Collagen alpha-1(I) chain Antibodies & ELISA Kits

PubMed ID: 10.3136/fstr.15.249, Protective Effect of Cartilage-selenium Polysaccharide on Diethylnitrosamine-Ind...
PubMed ID: 10.1186/s13395-018-0180-z, Myostatin and activin blockade by engineered follistatin results in hypertrophy ...
PubMed ID: 10.1111/php.13156, Protective Effects of Ginseng Proteins on Photoaging of Mouse Fibroblasts Induce...
PubMed ID: 10.1038/s41598-020-67514-4, Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in ...
PubMed ID: 10.1021/acsami.9b14800, Surface Epitaxial Crystallization-Directed Nanotopography for Accelerating Preos...
PubMed ID: 10.1016/j.tiv.2017.10.008, The excitotoxity of NMDA receptor NR2D subtype mediates human fetal lung fibrobl...
PubMed ID: 10.1016/j.jbc.2021.101479, Heparan sulfate is necessary for the early formation of nascent fibronectin and ...
PubMed ID: 10.1016/j.ejogrb.2020.01.027, Low expression of collagen type-1 in sacrouterine ligament as risk factor of sta...
PubMed ID: 10.1002/jat.3842, Food‐grade titanium dioxide (E171) by solid or liquid matrix administration in...
PubMed ID: 10.1002/cbf.3457, Uncarboxylated osteocalcin promotes osteogenic differentiation of mouse bone mar...
PubMed ID: 30888602, Wei X,Bao Y,Zhan X,Zhang L,Hao G,Zhou J,Chen Q.MiR-200a ameliorates peritoneal f...
PubMed ID: 31169440, Li X,Bu X,Yan F,Wang F,Wei D,Yuan J,Zheng W,Su J,Yuan J.Deletion of discoidin do...
PubMed ID: 31505422, Ge Y,Cheng R,Sun S,Zhang S,Li L,Jiang J,Yang C,Xuan X,Chen J.Fangxiao Formula al...
PubMed ID: 33992834, Feng Y,Dong H,Sun B,Hu Y,Yang Y,Jia Y,Jia L,Zhong X,Zhao R.METTL3/METTL14 transa...
PubMed ID: -, Yu WY,Cai W,Ying HZ, Zhang WY,Zhang HH,Yu CH.Exogenous Plant gma-miR-159a, Ident...
PubMed ID: -, Jennifer Bosco,Zhiwei Zhou,Sofie Gabriëls,Mayank Verma,Nan Liu,Brian K. Miller,...
PubMed ID: 33711827, Jiang Y,Liu JM,Huang JP,Lu KX,Sun WL,Tan JY,Li BX,Chen LL,Wu Y. Regeneration pot...
PubMed ID: -, Lombardi, F.; Augello, F.R.; Palumbo, P.; Mollsi, E.; Giuliani, M.; Cimini, A.M....
PubMed ID: 33721755, Zhou J,Li R,Liu Q,Zhang J,Huang H,Huang C,Zhang G,Zhao Y,Wu T,Tang Q,Huang Y,Zha...
PubMed ID: -, Lan Chen,Xiaofang Ji,Manni Wang et al.Involvement of TLR4 Signaling Regulated-CO...
PubMed ID: 33450323, Ma XL,Ding Y,Wu LM,Wang YX,Yao Y,Wang YX,Zhang YG,Niu JQ,He XX,Wang YQ.The gluca...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page