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- Table of Contents
Facts about Cytochrome c oxidase assembly factor 3 homolog, mitochondrial.
Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly. .
Human | |
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Gene Name: | COA3 |
Uniprot: | Q9Y2R0 |
Entrez: | 28958 |
Belongs to: |
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COA3 family |
coiled-coil domain containing 56; coiled-coil domain-containing protein 56; FLJ50764; HSPC009
Mass (kDA):
11.731 kDA
Human | |
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Location: | 17q21.2 |
Sequence: | 17; NC_000017.11 (42797625..42798704, complement) |
Mitochondrion inner membrane; Single-pass membrane protein.
PMID: 23260140 by Mick D.U., et al. MITRAC links mitochondrial protein translocation to respiratory-chain assembly and translational regulation.
PMID: 26321642 by Dennerlein S., et al. MITRAC7 acts as a COX1-specific chaperone and reveals a checkpoint during cytochrome c oxidase assembly.