Cannabinoid receptor 1 Antibodies

AND CNR1 ELISA kits, Cannabinoid receptor 1 Proteins

Many biological assays use antibodies to detect Cannabinoid receptor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cannabinoid receptor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cannabinoid receptor 1 antibodies...

We validate the specificity of these antibodies to Cannabinoid receptor 1 by testing them on tissues known to express CNR1 positively and negatively. Browse below to find the CNR1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CNR1 Infographic by Boster Bio

All CNR1 Products

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Figures

Specificity

Applications

Price

Anti-Cannabinoid Receptor I/CNR1 Antibody Picoband®

1 Citations 7 Q&As

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, ICC, WB

$370
Cat # A01291-1
100 μg/vial

Anti-Human Cannabinoid Receptor I DyLight® 488 conjugated CNR1 Antibody

6 Q&As

Human

Flow Cytometry

$515
Cat # A01291-Dyl488
100 μg/vial

Anti-Human Cannabinoid Receptor I DyLight® 550 conjugated CNR1 Antibody

14 Q&As

Human

Flow Cytometry

$515
Cat # A01291-Dyl550
100 μg/vial

Anti-Cannabinoid receptor 1/CNR1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A01291-2
100 µg/vial

CNR1 Overview

Facts about Cannabinoid receptor 1.

CNR1 3D structure. Source: alphafold

Cannabinoid receptor 1 (CNR1)

G-protein coupled receptor for endogenous cannabinoids (eCBs), such as N-arachidonoylethanolamide (also known as anandamide or AEA) and 2-arachidonoylglycerol (2-AG), in addition to phytocannabinoids, such as delta(9)-tetrahydrocannabinol (THC) (PubMed:15620723, PubMed:27768894, PubMed:27851727). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain.

Signaling typically involves reduction in cyclic AMP (PubMed:1718258, PubMed:21895628, PubMed:27768894). In the hypothalamus, might have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type.

Gene Information

Human
Gene Name:	CNR1
Uniprot:	P21554
Entrez:	1268

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

CANN6; CANN6CB1R; Cannabinoid R1; cannabinoid receptor 1 (brain); CannabinoidR1; CB1; CB1A; CB1K5; CB1R; CB-R; CB-RCB1cannabinoid receptor 1; central cannabinoid receptor; CNR; CNR1; SKR6R

Molecular Weight

Mass (kDA):
52.858 kDA

Genomic Context


Human

Location:	6q15
Sequence:	6; NC_000006.12 (88139864..88167349, complement)

Tissue Specificity

Widely expressed, with highest levels in fetal and adult brain. Expression levels of isoform 2 and isoform 3 are much lower than those of isoform 1.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Membrane raft. Mitochondrion outer membrane. Cell projection, axon. Cell junction, synapse, presynapse. Unexpectedly, in the mitochondria, the C-terminus is located in the mitochondrial intermembrane space, a compartment topologically considered as extracellular. In canonical seven-transmembrane G-protein coupled receptors, the C-terminus is cytosolic (By similarity). Found on presynaptic axon terminals in some GABAergic neurons in the somatosensory cortex (By similarity).