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Clarin-1 Antibodies

AND CLRN1 ELISA kits, Clarin-1 Proteins

Many biological assays use antibodies to detect Clarin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Clarin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Clarin-1 antibodies...

We validate the specificity of these antibodies to Clarin-1 by testing them on tissues known to express CLRN1 positively and negatively. Browse below to find the CLRN1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CLRN1 Infographic by Boster Bio

CLRN1 protein infographic

All CLRN1 Products

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CLRN1 (NM_174878) Human Over-expression Lysate

Human

$628
Cat # LS007401
100 µg

CLRN1 Overview

Facts about Clarin-1.

CLRN1 3D structure

CLRN1 3D structure. Source: alphafold

Clarin-1 (CLRN1)

May have a function in the excitatory ribbon synapse junctions between hair cells and cochlear ganglion cells and presumably also in similar synapses within the retina. .

Gene Information

Human
Gene Name:	CLRN1
Uniprot:	P58418
Entrez:	7401

Gene Information

Family

Belongs to:

clarin family

Family

Alternative Names

clarin 1; clarin-1; USH3; USH3AUsher syndrome type-3 protein; Usher syndrome 3A

Molecular Weight

Mass (kDA):
25.719 kDA

Molecular Weight

Genomic Context


Human

Location:	3q25.1
Sequence:	3; NC_000003.12 (150926163..150972999, complement)

Tissue Specificity

Widely expressed. Found in the retina.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Usher Syndrome
Retinitis Pigmentosa
Complete Hearing Loss
Sensorineural Hearing Loss (disorder)
Retinal Degeneration
Retinal Diseases
Vestibular Diseases
Visual Impairment
Deafness Congenital
Ear Diseases
Tissue Adhesions
Blind Vision

Circling Gait
Night Blindness
Branchio-oto-renal Syndrome
Waardenburg Syndrome
Biotinidase Deficiency
Macule
Ataxia

Disease

Pathways

Pathogenesis
Localization
Translation
Glycosylation
Cell-cell Adhesion
Cell Migration
Cell Development

Pigmentation
Regulation Of Gene Expression

Pathways

PTMs

Glycosylation

Cleavage

Research Areas

Vision

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLRN1

References

PMID: 11524702 by Joensuu T., et al. Mutations in a novel gene with transmembrane domains underlie Usher syndrome type 3.

PMID: 12145752 by Fields R.R., et al. Usher syndrome type III: revised genomic structure of the USH3 gene and identification of novel mutations.