This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Claudin-8.
Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. .
Human | |
---|---|
Gene Name: | CLDN8 |
Uniprot: | P56748 |
Entrez: | 9073 |
Belongs to: |
---|
claudin family |
claudin 8; Claudin8; Claudin-8; CLDN8; human CLDN8 gene for claudin-810claudin-8
Mass (kDA):
24.845 kDA
Human | |
---|---|
Location: | 21q22.11 |
Sequence: | 21; NC_000021.9 (30214006..30216097, complement) |
Expressed in the epididymis, mainly in the caput segment.
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells.
PMID: 17287494 by Dube E., et al. Gene expression profiling and its relevance to the blood-epididymal barrier in the human epididymis.
PMID: 22042635 by Uhlen M., et al. Antibody-based protein profiling of the human chromosome 21.