CIAO2B Antibodies

AND CIAO2B ELISA kits, CIAO2B Proteins

Many biological assays use antibodies to detect CIAO2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CIAO2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CIAO2B antibodies...

We validate the specificity of these antibodies to CIAO2B by testing them on tissues known to express CIAO2B positively and negatively. Browse below to find the CIAO2B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CIAO2B Infographic by Boster Bio

All CIAO2B Products

Product

Figures

Specificity

Applications

Price

Anti-FAM96B CIAO2B Antibody

Human, Mouse

$405
Cat # A32386
100ul

CIAO2B (NM_016062) Human Over-expression Lysate

Human

$628
Cat # LS051647
100 µg

CIAO2B Overview

Facts about Cytosolic iron-sulfur assembly component 2B.

CIAO2B 3D structure. Source: alphafold

Cytosolic iron-sulfur assembly component 2B (CIAO2B)

Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004, PubMed:22678362, PubMed:22678361). As a CIA complicated component and in collaboration with CIAO1 and MMS19, binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins (PubMed:23891004).

Included in the mitotic spindle- associated MMXD complicated it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD (PubMed:20797633). .

Gene Information

Human
Gene Name:	CIAO2B
Uniprot:	Q9Y3D0
Entrez:	51647

Family

Belongs to:

MIP18 family

Alternative Names

Cytosolic iron-sulfur assembly component 2B

Molecular Weight

Mass (kDA):
17.663 kDA

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (66932065..66934402, complement)

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton, spindle.

Interacting Proteins

CIAO1
MMS19

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CIAO2B

References

PMID: 20797633 by Ito S., et al. MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation.

PMID: 22678362 by Stehling O., et al. MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.