CHRNG Antibodies

AND CHRNG ELISA kits, CHRNG Proteins

Many biological assays use antibodies to detect CHRNG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRNG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRNG antibodies...

We validate the specificity of these antibodies to CHRNG by testing them on tissues known to express CHRNG positively and negatively. Browse below to find the CHRNG antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHRNG Infographic by Boster Bio

All CHRNG Products

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Anti-CHRNG Antibody

Human, Mouse, Rat

$405
Cat # A06571
100ul

CHRNG Overview

Facts about Acetylcholine receptor subunit gamma.

CHRNG 3D structure. Source: alphafold

Acetylcholine receptor subunit gamma (CHRNG)

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .

Gene Information

Human
Gene Name:	CHRNG
Uniprot:	P07510
Entrez:	1146

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

acetylcholine receptor subunit gamma; acetylcholine receptor, muscle, gamma subunit; ACHRG; cholinergic receptor, nicotinic, gamma; CHRNG; Nicotinic Acetylcholine R gamma; nicotinic, gamma polypeptide

Molecular Weight

Mass (kDA):
57.883 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (232539692..232548115)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Diseases

Pterygium
Multiple Pterygium Syndrome
Myasthenias
Pena-shokeir Syndrome Type I
Arthrogryposis
Rhabdomyosarcoma
Muscle Contracture
Myasthenic Syndromes, Congenital
Neoplasms
Soft Tissue Neoplasms
Hydrops Fetalis

Malignant Hyperpyrexia Due To Anesthesia
Sarcoma
Fetal Growth Retardation
Congenital Webbing
Tobacco Use Disorder
Fetal Diseases

Interacting Proteins

KRT31
KRTAP10-7
KRTAP10-8
KRTAP10-9
MDFI

MEOX2
NOTCH2NL
SPRY2

Pathways

Localization
Cell Development
Immune Response
Complement Activation
Pathogenesis
Innervation
Somite Development

Regulation Of Blood Pressure

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRNG

References

PMID: 3967651 by Shibahara S., et al. Cloning and sequence analysis of human genomic DNA encoding gamma subunit precursor of muscle acetylcholine receptor.

PMID: 7688301 by Beeson D.M.W., et al. Primary structure of the human muscle acetylcholine receptor. cDNA cloning of the gamma and epsilon subunits.