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CHRM1 Antibodies

AND CHRM1 ELISA kits, CHRM1 Proteins

Many biological assays use antibodies to detect CHRM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRM1 antibodies...

We validate the specificity of these antibodies to CHRM1 by testing them on tissues known to express CHRM1 positively and negatively. Browse below to find the CHRM1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHRM1 Infographic by Boster Bio

CHRM1 protein infographic

All CHRM1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Muscarinic Acetylcholine Receptor 1/CHRM1 Antibody Picoband®

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # A04081
100 μg/vial

CHRM1 (NM_000738) Human Over-expression Lysate

Human

$628
Cat # LS001128
100 µg

CHRM1 Overview

Facts about Muscarinic acetylcholine receptor M1.

CHRM1 3D structure

CHRM1 3D structure. Source: alphafold

Muscarinic acetylcholine receptor M1 (CHRM1)

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

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Gene Information

Human
Gene Name:	CHRM1
Uniprot:	P11229
Entrez:	1128

Gene Information

Family

Belongs to:

G-protein coupled receptor 1 family

Family

Alternative Names

cholinergic receptor, muscarinic 1; CHRM1; HM1; M1; M1R; mAChR M1; MGC30125; muscarinic acetylcholine receptor M1

Molecular Weight

Mass (kDA):
51.421 kDA

Molecular Weight

Genomic Context


Human

Location:	11q12.3
Sequence:	11; NC_000011.10 (62908675..62921861, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Schizophrenia
Myopia
Severe Myopia
Alzheimer's Disease
Malignant Neoplasms
Psychiatric Symptom
Scleral Diseases
Autoimmune Diseases
Mental Disorders
Depressive Disorder
Inflammation
Neurodegenerative Disorders
Nervousness

Asthma
Postmortem Changes
Cognition Disorders
Autoimmune Reaction
Cholangiocarcinoma
Autoimmunity
Stomach Neoplasms

Disease

Pathways

Cognition
Cell Proliferation
Transport
Endocytosis
Myelination
Membrane Depolarization
Fermentation
Sensitization
Receptor Internalization
Cell Growth

Pathogenesis
Epithelial Cell Proliferation
Gastric Acid Secretion
Acid Secretion
Secretion

Pathways

PTMs

Cleavage

Phosphorylation

Research Areas

Cell Cycle and Replication
GPCR
Neuronal Cell Markers
Neuroscience
Neurotransmission

Transcription Factors and Regulators

Research Areas

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRM1

References

PMID: 3697105 by Allard W.J., et al. Sequence of the gene encoding the human M1 muscarinic acetylcholine receptor.

PMID: 2336407 by Chapman C.G., et al. Isolation of the human ml (Hml) muscarinic acetylcholine receptor gene by PCR amplification.