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- Table of Contents
Facts about Centrosomal protein of 135 kDa.
Required for the recruitment of CEP295 into the proximal end of new-born centrioles in the centriolar microtubule wall during early S phase in a PLK4-dependent method. .
Human | |
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Gene Name: | CEP135 |
Uniprot: | Q66GS9 |
Entrez: | 9662 |
Belongs to: |
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CEP135/TSGA10 family |
Centrosomal protein of 135 kDa
Mass (kDA):
133.49 kDA
Human | |
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Location: | 4q12 |
Sequence: | 4; NC_000004.12 (55948808..56033361) |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles.
PMID: 17681131 by Kleylein-Sohn J., et al. Plk4-induced centriole biogenesis in human cells.
PMID: 18851962 by Kim K., et al. A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization.