CEACAM6 Antibodies

AND CEACAM6 ELISA kits, CEACAM6 Proteins

Many biological assays use antibodies to detect CEACAM6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEACAM6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEACAM6 antibodies...

We validate the specificity of these antibodies to CEACAM6 by testing them on tissues known to express CEACAM6 positively and negatively. Browse below to find the CEACAM6 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CEACAM6 Infographic by Boster Bio

All CEACAM6 Products

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Product

Figures

Specificity

Applications

Price

Anti-CEACAM6 (human) Monoclonal Antibody (9A6)

Human

ELISA

$896
Cat # M03197
100µg

Anti-CEACAM6 Rabbit Monoclonal Antibody

5 Q&As

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M03197-1
100 μl

Anti-CEACAM6 Antibody

Human, Mouse, Rat

$405
Cat # A03197
100ul

Anti-CEACAM6 Antibody

Human

IHC, WB

$380
Cat # A03197-1
100ul

Human CEACAM-6/CD66c Recombinant Protein

SDS-PAGE

$250
Cat # PROTP40199
Starting from 10ug

CEACAM6 Overview

Facts about Carcinoembryonic antigen-related cell adhesion molecule 6.

CEACAM6 3D structure. Source: alphafold

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)

Cell surface glycoprotein that plays a role in cell adhesion and tumor development (PubMed:2803308, PubMed:2022629, PubMed:1378450, PubMed:8776764, PubMed:11590190, PubMed:10910050, PubMed:14724575, PubMed:16204051). Intercellular adhesion occurs in a calcium- and fibronectin-independent manner (PubMed:2022629, PubMed:16204051).

Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). Plays a role in neutrophil adhesion to cytokine-activated endothelial cells (PubMed:1378450).

Gene Information

Human
Gene Name:	CEACAM6
Uniprot:	P40199
Entrez:	4680

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific crossreacting antigen); carcinoembryonic antigen-related cell adhesion molecule 6; CD66c antigen; CD66c; CEACAM6; CEACAM-6; CEAL; NCA; NCACEAL; Non-specific crossreacting antigen; Normal cross-reacting antigen

Molecular Weight

Mass (kDA):
37.195 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (41755529..41772211)

Tissue Specificity

Expressed in neutrophils (PubMed:1378450). Expressed in columnar epithelial and goblet cells of the colon (PubMed:10436421). Expressed in numerous tumor cell lines (at protein level) (PubMed:16204051).

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface. Localized to the apical glycocalyx surface.

Diseases

Tissue Adhesions
Malignant Neoplasms
Neoplasms
Adenocarcinoma
Carcinoma
Neoplasm Metastasis
Pancreatic Neoplasm
Leukemia
Crohn Disease
Pancreatic Adenocarcinoma
Malignant Neoplasm Of Pancreas
Cell Transformation, Neoplastic
Cell Invasion

Inflammation
Malignant Paraganglionic Neoplasm
Colorectal Cancer
Acute Lymphocytic Leukemia
Stomach Neoplasms
Inflammatory Bowel Diseases
Neoplasm Invasiveness

Interacting Proteins

CARTPT
CEACAM1
RHOXF2
UBQLN2
ZMYND19

Pathways

Cell Adhesion
Pathogenesis
Anoikis
Phagocytosis
Gene Silencing
Cell Proliferation
Localization
Neutrophil Activation
Cell Growth
Angiogenesis
Rna Interference
Immune Response
Virulence

Cell Differentiation
Secretion
Cell Migration
Endocytosis
Cell Death
Transport
Dna Hypermethylation

PTMs

Phosphorylation
Cleavage

Gpi Anchoring
Glycosylation

Methylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CEACAM6

References

PMID: 3220478 by Barnett T., et al. Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.

PMID: 3337731 by Tawaragi Y., et al. Primary structure of nonspecific crossreacting antigen (NCA), a member of carcinoembryonic antigen (CEA) gene family, deduced from cDNA sequence.