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CDKN1C Antibodies
AND CDKN1C ELISA kits, CDKN1C Proteins
Many biological assays use antibodies to detect CDKN1C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDKN1C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDKN1C antibodies...
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CDKN1C Infographic by Boster Bio
All CDKN1C Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
Flow Cytometry, IF, IHC
$486
Cat # M01244
100ug/vial
Cat # M01244
100ug/vial
Human, Mouse
ELISA
$480
Cat # EKC1428
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1428
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2267
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2267
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA, IF, IHC, WB
$380
Cat # A01244T310
100ul
Cat # A01244T310
100ul
Anti-p57 Kip2/CDKN1C Antibody Picoband®
1 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # A01244-2
100 μg/vial
Cat # A01244-2
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M01244-2
100 μl/vial
Cat # M01244-2
100 μl/vial
CDKN1C Overview
Facts about Cyclin-dependent kinase inhibitor 1C.
Cyclin-dependent kinase inhibitor 1C (CDKN1C)
Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation.
May play a role in maintenance of the non- proliferative state throughout life. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CDKN1C |
| Uniprot: | P49918 |
| Entrez: | 1028 |
Family
| Belongs to: |
|---|
| CDI family |
Alternative Names
Beckwith-Wiedemann syndrome; BWS; cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; KIP2BWCR; p57; p57Kip2; WBS
Molecular Weight
Mass (kDA):
32.177 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p15.4 |
| Sequence: | 11; NC_000011.10 (2883218..2885775, complement) |
Tissue Specificity
Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Beckwith-wiedemann Syndrome
- Carcinoma
- Cell Transformation, Neoplastic
- Hyperplasia
- Hydatidiform Mole
- Nephroblastoma
- Uterine Neoplasms
- Complete Hydatidiform Mole
- Partial Hydatidiform Mole
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- FBXL12
- MCM7
Pathways
- Cell Cycle
- Methylation
- Cell Proliferation
- Dna Methylation
- Cell Cycle Arrest
- Pathogenesis
- Cell Differentiation
- Cell Growth
- Senescence
- Cell Death
- Localization
- S Phase
- Gene Silencing
PTMs
- Methylation
- Phosphorylation
- Acetylation
- Reduction
- Cleavage
Research Areas
- Breast Cancer
- Cancer
- Cell Cycle and Replication
- Core ESC-Like Genes
- DNA Repair
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDKN1C
bosterbio.com/bosterbio-gene-info-cards/CDKN1C
References
PMID: 7729684 by Matsuoka S., et al. p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
PMID: 8640800 by Reid L.H., et al. Genomic organization of the human p57KIP2 gene and its analysis in the G401 Wilms' tumor assay.
1 Publications of Boster CDKN1C Antibodies & ELISA Kits
- PubMed ID: 10.1177/1933719117725823, miR-3074-5p Promotes the Apoptosis but Inhibits the Invasiveness of Human Extrav...
*More publications can be found for each product on its corresponding product page