Cyclin-dependent kinase 3 Antibodies

AND CDK3 ELISA kits, Cyclin-dependent kinase 3 Proteins

Many biological assays use antibodies to detect Cyclin-dependent kinase 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cyclin-dependent kinase 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cyclin-dependent kinase 3 antibodies...

We validate the specificity of these antibodies to Cyclin-dependent kinase 3 by testing them on tissues known to express CDK3 positively and negatively. Browse below to find the CDK3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDK3 Infographic by Boster Bio

All CDK3 Products

Product

Figures

Specificity

Applications

Price

Anti-Cyclin-dependent kinase 3 CDK3 Antibody

Human, Mouse, Rat

$405
Cat # A08097
100ul

Human CDK3 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ00526
Starting from 10ug

CDK3 (NM_001258) Human Over-expression Lysate

Human

$628
Cat # LS001018
100 µg

CDK3 Overview

Facts about Cyclin-dependent kinase 3.

CDK3 3D structure. Source: alphafold

Cyclin-dependent kinase 3 (CDK3)

Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0- G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase.

Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation.

Gene Information

Human
Gene Name:	CDK3
Uniprot:	Q00526
Entrez:	1018

Family

Belongs to:

protein kinase superfamily

Alternative Names

Cell division protein kinase 3; cyclin-dependent kinase 3; EC 2.7.11; EC 2.7.11.22

Molecular Weight

Mass (kDA):
35.046 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (76000906..76005999)

Tissue Specificity

Expressed in cancer cell lines and glioblastoma tissue.

Diseases

Malignant Neoplasms
Neoplasms
Cell Transformation, Neoplastic
Carcinoma
Malignant Neoplasm Of Breast
Mammary Neoplasms
Glioblastoma
Metaplastic Cell Transformation
Lymphatic Diseases
Fracture Of First Cervical Vertebra
Diabetic Nephropathy
Classical Hodgkin's Lymphoma
Tumor Progression

Tumors Of Adrenal Cortex
Sequelae Aspects
Malignant Neoplasm Of Lung
Carcinogenesis
Carcinoid Tumor
Parasitic Diseases
Multiple Myeloma

Interacting Proteins

CCNC
CDKN1A
CKS1B
CKS2
HSP90AB1

Pathways

Cell Cycle
Cell Proliferation
Cell Division
Cell Death
S Phase
G1 Phase
Regulation Of Gene Expression
Drug Resistance
Dna Replication
Regulation Of Cell Cycle
Hyperphosphorylation
Programmed Cell Death
Cell Cycle Phase

Dna Repair
Cell Cycle Arrest
Reverse Transcription
Mrna Transcription
Cell Growth
Invasive Growth
Pathogenesis

PTMs

Phosphorylation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDK3

References

PMID: 1639063 by Meyerson M., et al. A family of human cdc2-related protein kinases.

PMID: 8846921 by Hofmann F., et al. Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit.