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- Table of Contents
Facts about Cyclin-dependent kinase 16.
Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis.
Human | |
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Gene Name: | CDK16 |
Uniprot: | Q00536 |
Entrez: | 5127 |
Belongs to: |
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protein kinase superfamily |
Cell division protein kinase 16; cyclin-dependent kinase 16; EC 2.7.11; EC 2.7.11.22; FLJ16665; PCTAIRE protein kinase 1; PCTAIRE; PCTAIRE1; PCTAIRE-motif protein kinase 1; PCTGAIRE; PCTK1Serine/threonine-protein kinase PCTAIRE-1
Mass (kDA):
55.716 kDA
Human | |
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Location: | Xp11.3 |
Sequence: | X; NC_000023.11 (47217881..47229997) |
Detected in pancreas islets (at protein level). Detected in brain and pancreas.
Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, synaptosome. Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY.
PMID: 1639063 by Meyerson M., et al. A family of human cdc2-related protein kinases.
PMID: 22796189 by Shehata S.N., et al. Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase.