Cadherin-8 Antibodies

AND CDH8 ELISA kits, Cadherin-8 Proteins

Many biological assays use antibodies to detect Cadherin-8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cadherin-8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cadherin-8 antibodies...

We validate the specificity of these antibodies to Cadherin-8 by testing them on tissues known to express CDH8 positively and negatively. Browse below to find the CDH8 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDH8 Infographic by Boster Bio

All CDH8 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CDH8/Cadherin 8 Antibody

3 Q&As

Human, Mouse, Rat

IF, IHC, WB

$360
Cat # A09584
100 µl

Cadherin 8 (CDH8) (NM_001796) Human Recombinant Protein

$1062
Cat # PROTP55286
20 µg

Cadherin 8 (CDH8) (NM_001796) Human Over-expression Lysate

Human

$960
Cat # LS001006
100 µg

CDH8 Overview

Facts about Cadherin-8.

CDH8 3D structure. Source: alphafold

Cadherin-8 (CDH8)

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Gene Information

Human
Gene Name:	CDH8
Uniprot:	P55286
Entrez:	1006

Family

Belongs to:

No superfamily

Alternative Names

cadherin 8, type 2; Cadherin8; Cadherin-8; CDH8; Nbla04261; putative protein product of Nbla04261

Molecular Weight

Mass (kDA):
88.253 kDA

Genomic Context


Human

Location:	16q21
Sequence:	16; NC_000016.10 (61640398..62036446, complement)

Tissue Specificity

Mainly expressed in brain. Found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Tissue Adhesions
Nervousness
Autistic Disorder
Muscular Fasciculation
Carcinoma
Malignant Neoplasms
Neoplasms
Schizophrenia
Mental Disorders
Autism Spectrum Disorders
Learning Disorders
Neoplasm Metastasis
Stage I Non-small Cell Lung Cancer

Malignant Neoplasm Of Breast
Learning Disabilities
Stage I Lung Cancer
Kidney Neoplasm
Neoplasm Invasiveness
Malignant Neoplasm Of Lung
Carcinogenesis

Pathways

Cell Adhesion
Localization
Brain Development
Neurogenesis
Regionalization
Cell-cell Adhesion
Cell-cell Recognition
Induction Of Apoptosis
Regulation Of Gene Expression
Energy Homeostasis
Kidney Morphogenesis
Cell Death

Tissue Remodeling
Cell Differentiation
Social Behavior
Pathogenesis
Secretion
Kidney Development

PTMs

Cleavage on pair of basic residues

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDH8

References

PMID: 10861224 by Shimoyama Y., et al. Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins.

PMID: 7982033 by Tanihara H., et al. Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin.