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CDC45 Antibodies
AND CDC45 ELISA kits, CDC45 Proteins
Many biological assays use antibodies to detect CDC45, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC45 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC45 antibodies...
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CDC45 Infographic by Boster Bio
All CDC45 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01367
100 μl
Cat # M01367
100 μl
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M01367-2
100 μg/vial
Cat # M01367-2
100 μg/vial
CDC45 Overview
Facts about Cell division control protein 45 homolog.
Cell division control protein 45 homolog (CDC45)
Required for initiation of chromosomal DNA replication. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CDC45 |
| Uniprot: | O75419 |
| Entrez: | 8318 |
Family
| Belongs to: |
|---|
| CDC45 family |
Alternative Names
CDC45 cell division cycle 45-like (S. cerevisiae); cell division cycle 45 homolog (S. cerevisiae); cell division cycle 45-like 2; human CDC45; S.cerevisiae, homolog)-like
Molecular Weight
Mass (kDA):
65.569 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q11.21 |
| Sequence: | 22; NC_000022.11 (19479294..19520612) |
Tissue Specificity
Widely expressed, highest levels are found in adult testis and thymus and in fetal liver.
Subcellular Localizations
Cytoplasm. Nucleus.
Diseases
- Malignant Neoplasms
- Genomic Instability
- Neoplasms
- Digeorge Syndrome
- Physiological Stress
- Retinoblastoma
- Schizophrenia
- Malignant Neoplasm Of Breast
- Ataxia Telangiectasia
- Genotoxic Stress
- Craniofacial Abnormalities
- Congenital Heart Defects
Interacting Proteins
- CDKN1A
- CEP55
- CLSPN
- MCM2
- RPA2
- TOPBP1
Pathways
- Dna Replication
- Cell Cycle
- S Phase
- Localization
- G1 Phase
- Mitosis
- Dna Replication Initiation
- Cell Division
- Cell Proliferation
- Dna Repair
- Cell Growth
- Dna Replication Checkpoint
- Hyperphosphorylation
PTMs
- Phosphorylation
- Ubiquitination
- Cleavage
- Methylation
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC45
bosterbio.com/bosterbio-gene-info-cards/CDC45
References
PMID: 9755170 by Mimura S., et al. Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk.
PMID: 9660782 by Saha P., et al. The human homolog of Saccharomyces cerevisiae CDC45.