CDC42BPA Antibodies

AND CDC42BPA ELISA kits, CDC42BPA Proteins

Many biological assays use antibodies to detect CDC42BPA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC42BPA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC42BPA antibodies...

We validate the specificity of these antibodies to CDC42BPA by testing them on tissues known to express CDC42BPA positively and negatively. Browse below to find the CDC42BPA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDC42BPA Infographic by Boster Bio

All CDC42BPA Products

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Product

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Specificity

Applications

Price

Anti-CDC42BPA Antibody

Human, Mouse

$405
Cat # A05509
100ul

CDC42 binding protein kinase alpha (CDC42BPA) (NM_014826) Human Over-expression Lysate

Human

$960
Cat # LS008476
100 µg

CDC42BPA Overview

Facts about Serine/threonine-protein kinase MRCK alpha.

CDC42BPA 3D structure. Source: alphafold

Serine/threonine-protein kinase MRCK alpha (CDC42BPA)

Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration (PubMed:15723050, PubMed:9418861, PubMed:9092543). Regulates actin cytoskeletal reorganization through phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715).

In concert with MYO18A and LURAP1, is involved in regulating lamellar actomyosin retrograde flow that's imperative to cell protrusion and migration (PubMed:18854160). Phosphorylates: PPP1R12A, LIMK1 and LIMK2 (PubMed:11340065, PubMed:11399775).

Gene Information

Human
Gene Name:	CDC42BPA
Uniprot:	Q5VT25
Entrez:	8476

Family

Belongs to:

protein kinase superfamily

Alternative Names

CDC42 binding protein kinase alpha (DMPK-like); CDC42 binidng protein kinase beta; CDC42-binding protein kinase alpha (DMPK-like); CDC42-binding protein kinase alpha; DMPK-like alpha; EC 2.7.11; EC 2.7.11.1; KIAA0451DKFZp686L1738; MRCK alpha; MRCK; MRCKADKFZp686P1738; Myotonic dystrophy kinase-related CDC42-binding kinase alpha; myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; Myotonic dystrophy protein kinase-like alpha; PK428FLJ23347; serine/threonine-protein kinase MRCK alpha; ser-thr protein kinase PK428; ser-thr protein kinase related to the myotonic dystrophy protein

Molecular Weight

Mass (kDA):
197.307 kDA

Genomic Context


Human

Location:	1q42.13
Sequence:	1; NC_000001.11 (226989858..227318502, complement)

Tissue Specificity

Abundant in the heart, brain, skeletal muscle, kidney, and pancreas, with little or no expression in the lung and liver.

Subcellular Localizations

Cytoplasm. Cell projection, lamellipodium. Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent. Localizes in the lamellipodium in a FAM89B/LRAP25-dependent manner.