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- Table of Contents
, No Gclids
CDC42 Antibodies
AND CDC42 ELISA kits, CDC42 Proteins
Many biological assays use antibodies to detect CDC42, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDC42 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDC42 antibodies...
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CDC42 Infographic by Boster Bio
All CDC42 Products
Product
Figures
Specificity
Applications
Price
Anti-CDC42 Antibody Picoband®
1 Citations 17 Q&As
Bovine, Human, Mouse, Rat
IHC, WB
$370
Cat # PA1366
100 μg/vial
Cat # PA1366
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IHC, WB
$370
Cat # M00119
100 μl
Cat # M00119
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00119
100 μg/vial
Cat # A00119
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00119-1
100 µg/vial
Cat # A00119-1
100 µg/vial
CDC42 Overview
Facts about Cell division control protein 42 homolog.
Cell division control protein 42 homolog (CDC42)
In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes.
Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia.
Gene Information
| Human | |
|---|---|
| Gene Name: | CDC42 |
| Uniprot: | P60953 |
| Entrez: | 998 |
Family
| Belongs to: |
|---|
| small GTPase superfamily |
Alternative Names
CDC42; CDC42Hs; cell division control protein 42 homolog; cell division cycle 42 (GTP binding protein, 25kDa); cell division cycle 42 (GTP-binding protein, 25kD); dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K GTP-binding protein; G25K; growth-regulating protein; GTP-binding protein, 25kD; small GTP binding protein CDC42
Molecular Weight
Mass (kDA):
21.259 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.12 |
| Sequence: | 1; NC_000001.11 (22052709..22101360) |
Subcellular Localizations
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Cell projection, dendrite. Localizes to spindle during prometaphase cells. Moves to the central spindle as cells progressed through anaphase to telophase (PubMed:15642749). Localizes at the end of cytokinesis in the intercellular bridge formed between two daughter cells (PubMed:15642749). Its localization is regulated by the activities of guanine nucleotide exchange factor ECT2 and GTPase activating protein RACGAP1 (PubMed:15642749). Colo
Diseases
- Tissue Adhesions
- Malignant Neoplasms
- Neoplasms
- Cell Invasion
- Neoplasm Metastasis
- Cell Transformation, Neoplastic
- Wiskott-aldrich Syndrome
- Carcinoma
- Neoplasm Invasiveness
- Nervousness
- Malignant Neoplasm Of Breast
- Malignant Paraganglionic Neoplasm
- Inflammation
Interacting Proteins
- ABCA1
- APC
- ARHGAP1
- ARHGEF7
- BAIAP2
- CDC42BPA
- CDC42EP1
- CDC42EP2
- IQGAP1
- ITSN1
Pathways
- Cell Migration
- Localization
- Cell Motility
- Cell Cycle
- Secretion
- Cell Adhesion
- Cell Proliferation
- Cell Growth
- Cell Division
- Endocytosis
- Cytokinesis
- Transport
- Phagocytosis
PTMs
- Phosphorylation
- Ribosylation
- Cleavage
- Prenylation
- Dephosphorylation
- Ubiquitination
- Geranylgeranylation
- Deamidation
- Methylation
- Myristoylation
Research Areas
- Breast Cancer
- Cancer
- Phospho-Specific
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDC42
bosterbio.com/bosterbio-gene-info-cards/CDC42
References
PMID: 2122236 by Munemitsu S., et al. Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42.
PMID: 2124704 by Shinjo K., et al. Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.
1 Publications of Boster CDC42 Antibodies & ELISA Kits
- PubMed ID: 28934273, Han F1, Zhuang TT1, Chen JJ1, Zhu XL1,2, Cai YF1, Lu YP1. PLoS One. 2017 Sep 21;...
*More publications can be found for each product on its corresponding product page