CD59 glycoprotein Antibodies

AND CD59 ELISA kits, CD59 glycoprotein Proteins

Many biological assays use antibodies to detect CD59 glycoprotein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD59 glycoprotein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD59 glycoprotein antibodies...

We validate the specificity of these antibodies to CD59 glycoprotein by testing them on tissues known to express CD59 positively and negatively. Browse below to find the CD59 antibody that suites your experiment. We have 15 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CD59 Infographic by Boster Bio

All CD59 Products

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Product

Figures

Specificity

Applications

Price

Anti-CD59 glycoprotein CD59 Antibody Picoband®

5 Q&As

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # RP1076
100 μg/vial

Anti-human CD59 Monoclonal Antibody APC Conjugated, Flow Validated

10 Q&As

Human

Flow Cytometry

$325
Cat # FC00914-APC
100 tests, 200 tests

Anti-human CD59 Monoclonal Antibody Biotin Conjugated, Flow Validated

10 Q&As

Human

Flow Cytometry

$299
Cat # FC00914-Biotin
100ug

Anti-human CD59 Monoclonal Antibody FITC Conjugated, Flow Validated

Human

Flow Cytometry

$235
Cat # FC00914-FITC
100 tests, 200 tests

Anti-human CD59 Monoclonal Antibody PE Conjugated, Flow Validated

2 Q&As

Human

Flow Cytometry

$299
Cat # FC00914-PE
100 tests, 200 tests

Anti-human CD59 Monoclonal Antibody Unconjugated, Flow Validated

10 Q&As

Human

Flow Cytometry

$158
Cat # FC00914
100ug, 500ug

Anti-CD59 / Complement Regulatory Protein / Protectin Monoclonal Antibody

16 Q&As

Human

IHC

$486
Cat # M00914
100ug/vial

Anti-CD59 Rabbit Monoclonal Antibody

15 Q&As

Human

Flow Cytometry, IP, IF, ICC, WB

$370
Cat # M00914-1
100 μl

Anti-CD59 Antibody Picoband®(monoclonal, 3C10)

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M00914-2
100 μg/vial

Anti-CD59 glycoprotein CD59 Antibody

Human, Mouse

ELISA, WB

$449
Cat # A00914-1
0.1 mg

Anti-Hu CD59 Purified Monoclonal Antibody

Human, Mouse

Flow Cytometry, IP, IHC-P, WB

$299
Cat # M00914-3
0.1 mg

Anti-CD59 glycoprotein CD59 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A00914-2
100ul

Anti-Cd59 Antibody

Mouse, Rat

IHC

$370
Cat # A00914-3
100 μg/vial

Human CD59 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP13987
Starting from 4ug

CD59 (NM_203330) Human Over-expression Lysate

Human

$628
Cat # LS000966
100 µg

CD59 Overview

Facts about CD59 glycoprotein.

CD59 3D structure. Source: alphafold

CD59 glycoprotein (CD59)

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 needed for complete formation of the osmolytic pore.

This inhibitor seems to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Gene Information

Human
Gene Name:	CD59
Uniprot:	P13987
Entrez:	966

Family

Belongs to:

No superfamily

Alternative Names

16.3A5; 1F5 antigen; 1F5; 20 kDa homologous restriction factor; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16; CD59 antigen; CD59 antigen, complement regulatory protein; CD59 glycoprotein; CD59 molecule, complement regulatory protein; CD59; EJ16; EJ30; EJ30, EL32 and G344); EL32; FLJ38134; FLJ92039; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MAC-IP; MEM43 antigen; MEM43; membrane attack complex (MAC) inhibition factor; Membrane attack complex inhibition factor; Membrane in

Molecular Weight

Mass (kDA):
14.177 kDA

Genomic Context


Human

Location:	11p13
Sequence:	11; NC_000011.10 (33703010..33736479, complement)

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Soluble form found in a number of tissues.

Diseases

Paroxysmal Nocturnal Hemoglobinuria
Hemoglobinuria
Hemoglobinuria, Paroxysmal
Hemolysis (disorder)
Neoplasms
Anemia
Malignant Neoplasms
Inflammation
Aplastic Anemia
Tissue Adhesions
Leukemia
Thrombosis
Carcinoma

Anemia, Hemolytic
Lymphoma
Autoimmune Reaction
Malignant Paraganglionic Neoplasm
Dysmyelopoietic Syndromes
Pancytopenia
Hematological Disease

Interacting Proteins

TMED2

Pathways

Complement Activation
Pathogenesis
Cytolysis
Cell Activation
Immune Response
Localization
Cell Death
Secretion
Glycosylation
Cell Proliferation
T Cell Activation
Complement-dependent Cytotoxicity
Inflammatory Response

Endocytosis
Transport
Phagocytosis
Cell Adhesion
Cell Killing
Coagulation
Regeneration

PTMs

Glycosylation
Cleavage
Gpi Anchoring
Phosphorylation
Acylation
Biotinylation
Deamination
Ubiquitination

Acetylation
Dephosphorylation
Oxidation
Methylation
Geranylgeranylation
Ribosylation
Reduction
Deglycosylation

Research Areas

Cell Biology
Cellular Markers
Immunology
Signal Transduction
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD59

References

PMID: 2475570 by Davies A., et al. CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.

PMID: 1689664 by Philbrick W.M., et al. The CD59 antigen is a structural homologue of murine Ly-6 antigens but lacks interferon inducibility.