CD58 Antibodies

AND CD58 ELISA kits, CD58 Proteins

Many biological assays use antibodies to detect CD58, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD58 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD58 antibodies...

We validate the specificity of these antibodies to CD58 by testing them on tissues known to express CD58 positively and negatively. Browse below to find the CD58 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CD58 Infographic by Boster Bio

All CD58 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LFA3/CD58 Antibody Picoband®

3 Q&As

Human

Flow Cytometry, IHC, WB

$370
Cat # RP1106
100 μg/vial

Anti-CD58 Antibody

Human, Mouse, Rat

$405
Cat # A02800
100ul

LFA3 (CD58) (NM_001779) Human Recombinant Protein

$1249
Cat # PROTP19256
20 µg

Anti-CD58 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IP, WB

$370
Cat # M02800
100 μl/vial

Human CD58 ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2151
96 wells/kit, with removable strips.

CD58 Overview

Facts about Lymphocyte function-associated antigen 3.

CD58 3D structure. Source: alphafold

Lymphocyte function-associated antigen 3 (CD58)

Ligand of the T-lymphocyte CD2 glycoprotein.
This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen- presenting cells and the T-lymphocyte rosetting with erythrocytes.

In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. .

Gene Information

Human
Gene Name:	CD58
Uniprot:	P19256
Entrez:	965

Family

Belongs to:

No superfamily

Alternative Names

Ag3; CD58 antigen; CD58 antigen, (lymphocyte function-associated antigen 3); CD58 molecule; CD58; FLJ23181; FLJ43722; LFA3; LFA-3; LFA3ag3; lymphocyte function-associated antigen 3; Surface glycoprotein LFA-3

Molecular Weight

Mass (kDA):
28.147 kDA

Genomic Context


Human

Location:	1p13.1
Sequence:	1; NC_000001.11 (116500390..116571093, complement)

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.

Diseases

Tissue Adhesions
Neoplasms
Leukemia
Malignant Neoplasms
Carcinoma
Malignant Paraganglionic Neoplasm
Inflammation
Lymphoma
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Acute Lymphocytic Leukemia
Autoimmune Reaction
Sclerosis

Melanoma
Burkitt Lymphoma
Autoimmune Diseases
Immunologic Deficiency Syndromes
Multiple Sclerosis
Lymphoid Leukemia
Paroxysmal Nocturnal Hemoglobinuria

Pathways

Cell Adhesion
Cell Activation
T Cell Activation
Immune Response
Cell Proliferation
Secretion
Pathogenesis
T Cell Proliferation
Cytokine Production
Cytolysis
Lymphocyte Activation
Cell-cell Adhesion
Cell Growth

Cell Cycle
Localization
Cell Differentiation
Cytokine Secretion
Cell Death
Conjugation
Lymphocyte Proliferation

PTMs

Phosphorylation
Glycosylation
Biotinylation
Cleavage
Deglycosylation

Gpi Anchoring
Acetylation
Methylation
Demethylation
Reduction

Dephosphorylation

Research Areas

Cell Biology
Cellular Markers
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD58

References

PMID: 3309127 by Wallner B.P., et al. Primary structure of lymphocyte function-associated antigen 3 (LFA- 3). The ligand of the T lymphocyte CD2 glycoprotein.

PMID: 3313052 by Seed B.; An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2.