CD320 antigen Antibodies

AND CD320 ELISA kits, CD320 antigen Proteins

Many biological assays use antibodies to detect CD320 antigen, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD320 antigen in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD320 antigen antibodies...

We validate the specificity of these antibodies to CD320 antigen by testing them on tissues known to express CD320 positively and negatively. Browse below to find the CD320 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CD320 Infographic by Boster Bio

All CD320 Products

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Specificity

Applications

Price

Human CD320 / 8D6A / TCblR ELISA Kit PicoKine®

11 Q&As

Human

ELISA

$750
Cat # EK1255
96 wells/kit, with removable strips.

Anti-CD320 antigen CD320 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A06409
100ul

Human CD320/TCblR/8D6A Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9NPF0
Starting from 10ug

Human CD320/8D6A PicoKine® Quick ELISA Kit

Human

ELISA

$499
Cat # FEK1255
96 wells/kit, with removable strips.

CD320 Overview

Facts about CD320 antigen.

CD320 3D structure. Source: alphafold

CD320 antigen (CD320)

Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389). Plays an essential role in cobalamin uptake (PubMed:18779389, PubMed:20524213).

Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal centre B cells (PubMed:10727470). Functions as costimulator to promote B cell responses to antigenic stimulation; promotes B cell differentiation and proliferation (PubMed:10727470, PubMed:11418631).

Gene Information

Human
Gene Name:	CD320
Uniprot:	Q9NPF0
Entrez:	51293

Family

Belongs to:

No superfamily

Alternative Names

8D6 antigen; 8D6A; 8D6AFDC-SM-8D6; CD320 antigenFDC-signaling molecule 8D6,8D6TCBLR; CD320 molecule; CD320; TCblR; Transcobalamin receptor

Molecular Weight

Mass (kDA):
28.991 kDA

Genomic Context


Human

Location:	19p13.2
Sequence:	19; NC_000019.10 (8302127..8308358, complement)

Tissue Specificity

Detected in the germinal center (GC) of lymphoid follicles (at protein level) (PubMed:11418631). Expressed abundantly on follicular dendritic cells (FDCs) (PubMed:10727470).

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Malignant Neoplasms
Acquired Immunodeficiency Syndrome
Adenocarcinoma
Neoplasms
Colorectal Neoplasms
Nervousness
Inborn Errors Of Metabolism
Hiv Infections

Tissue Adhesions
Methylmalonic Acidemia
Vitamin B 12 Deficiency

Pathways

Cell Adhesion
Methylation
Transport
Cell Division
Cell Proliferation
Dna Hypomethylation
Cell Cycle
Dna Methylation

Neurogenesis
Endocytosis

PTMs

Biotinylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD320

References

PMID: 10727470 by Li L., et al. Identification of a human follicular dendritic cell molecule that stimulates germinal center B cell growth.

PMID: 11418631 by Zhang X., et al. The distinct roles of T cell-derived cytokines and a novel follicular dendritic cell-signaling molecule 8D6 in germinal center-B cell differentiation.