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- Table of Contents
Facts about CD2-associated protein.
May play a role in receptor clustering and cytoskeletal polarity at the junction between T-cell and antigen-presenting cell (PubMed:9741631). May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus (PubMed:10514378).
Mouse | |
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Gene Name: | Cd2ap |
Uniprot: | Q9JLQ0 |
Entrez: | 12488 |
Belongs to: |
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No superfamily |
adapter protein CMS; Cas ligand with multiple Src homology 3 (SH3) domains; CD2AP; CD2-associated protein; CMS; DKFZp586H0519
Mass (kDA):
70.45 kDA
Mouse | |
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Location: | 17|17 B3 |
Sequence: | 17; |
Expressed in podocytes (at protein level).
PMID: 9741631 by Dustin M.L., et al. A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts.
PMID: 10913159 by Lehtonen S., et al. In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2.