CD207 Antibodies

AND CD207 ELISA kits, CD207 Proteins

Many biological assays use antibodies to detect CD207, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD207 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD207 antibodies...

We validate the specificity of these antibodies to CD207 by testing them on tissues known to express CD207 positively and negatively. Browse below to find the CD207 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CD207 Infographic by Boster Bio

All CD207 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CD207 Antibody

Human, Mouse, Rat

$405
Cat # A02316-1
100ul

Human Langerin/CD207 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9UJ71
Starting from 10ug

Anti-Langerin (CD207) Rabbit Monoclonal Antibody

Human

IHC

$370
Cat # M02316-2
100 μl/vial

Human Langerin/CD207 ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2162
96 wells/kit, with removable strips.

Langerin (CD207) (NM_015717) Human Over-expression Lysate

Human

$628
Cat # LS050489
100 µg

CD207 Overview

Facts about C-type lectin domain family 4 member K.

CD207 3D structure. Source: alphafold

C-type lectin domain family 4 member K (CD207)

Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a powerful regulator of membrane superimposition and zippering.

Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.

Gene Information

Human
Gene Name:	CD207
Uniprot:	Q9UJ71
Entrez:	50489

Family

Belongs to:

No superfamily

Alternative Names

CD207 antigen; CD207 antigen, langerin; CD207 molecule, langerin; CD207; CLEC4KLangerhans cell specific c-type lectin; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerin

Molecular Weight

Mass (kDA):
36.725 kDA

Genomic Context


Human

Location:	2p13.3
Sequence:	2; NC_000002.12 (70825248..70860787, complement)

Tissue Specificity

Exclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.

Subcellular Localizations

Membrane; Single-pass type II membrane protein. Found in Birbeck granules (BGs), which are organelles consisting of superimposed and zippered membranes.

Diseases

Neoplasms
Histiocytosis, Langerhans-cell
Inflammation
Histiocytosis
Hiv Infections
Diphtheria
Contact Dermatitis
Contact Hypersensitivity
Carcinoma
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Infective Disorder

Dermatitis
Tissue Adhesions
Dermatologic Disorders
Immunologic Deficiency Syndromes
Sarcoma
Decreased Immunologic Activity [pe]
Lymphoma

Interacting Proteins

GRAMD2B

Pathways

Immune Response
Pathogenesis
Hypersensitivity
Localization
Transport
Cell Activation
Endocytosis
Sensitization
Cell Differentiation
Adaptive Immune Response
Secretion
Cytokine Production
Cell Adhesion

Cell Migration
T Cell Activation
Mast Cell Activation
Wound Healing
Receptor-mediated Endocytosis
Skin Morphogenesis
Cell Proliferation

PTMs

Glycosylation

Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD207

References

PMID: 10661407 by Valladeau J., et al. Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules.

PMID: 12626394 by Stambach N.S., et al. Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells.