CD101 Antibodies

AND CD101 ELISA kits, CD101 Proteins

Many biological assays use antibodies to detect CD101, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD101 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD101 antibodies...

We validate the specificity of these antibodies to CD101 by testing them on tissues known to express CD101 positively and negatively. Browse below to find the CD101 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CD101 Infographic by Boster Bio

All CD101 Products

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Product

Figures

Specificity

Applications

Price

Anti-Hu CD101 Purified Monoclonal Antibody

Human

Flow Cytometry, IP, IHC-F, WB

$299
Cat # M07106
0.1 mg

Anti-CD101 Antibody

Human, Mouse, Rat

$405
Cat # A07106
100ul

Anti-CD101 Antibody

Human

ELISA, IHC

$370
Cat # A07106-1
100 μg/vial

CD101 (NM_004258) Human Over-expression Lysate

Human

$960
Cat # LS009398
100 µg

CD101 Overview

Facts about Immunoglobulin superfamily member 2.

CD101 3D structure. Source: alphafold

Immunoglobulin superfamily member 2 (CD101)

Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on triggered T-cells and secretion of IL2.

Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and following CD3- induced changes in intracellular free calcium.

Gene Information

Human
Gene Name:	CD101
Uniprot:	Q93033
Entrez:	9398

Family

Belongs to:

No superfamily

Alternative Names

CD101 antigen; CD101 molecule; CD101; Cell surface glycoprotein V7; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; IGSF2; Leukocyte Surface Protein; member 2; V7

Molecular Weight

Mass (kDA):
115.109 kDA

Genomic Context


Human

Location:	1p13.1
Sequence:	1; NC_000001.11 (116987997..117037481)

Tissue Specificity

Expressed in lung, thymus and small intestine. Detected in cutaneous dendritic cells, activated T-cells, monocytes and granulocytes as well as with epithelial cells with dendritic morphology. Expressed in some leukemic cells, the CD4(+) CD56(+) blastic tumor cells, as well as in Langerhans cells from LCH (Langerhans cell histiocytosis) patients.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Insulin-dependent
Autoimmune Reaction
Autoimmunity
Autoimmune Diseases
Sclerosis
Liver Diseases
Hepatitis, Autoimmune
Inflammatory Bowel Diseases
Lung Diseases
Immunologic Tolerance
Intestinal Diseases
Lung Diseases, Interstitial

Histiocytosis
Malignant Neoplasms
Neoplasms
Histiocytosis, Langerhans-cell
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Diabetes, Autoimmune

Pathways

Cell Activation
T Cell Activation
Bioluminescence
Cell Proliferation
Chemotaxis
Cell Motility
T Cell Proliferation
Glycosylation

Localization
Secretion

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD101

References

PMID: 7722300 by Ruegg C.L., et al. V7, a novel leukocyte surface protein that participates in T cell activation. II. Molecular cloning and characterization of the V7 gene.

PMID: 7722299 by Rivas A., et al. V7, a novel leukocyte surface protein that participates in T cell activation. I. Tissue distribution and functional studies.