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- Table of Contents
, No Gclids
CCT2 Antibodies
AND CCT2 ELISA kits, CCT2 Proteins
Many biological assays use antibodies to detect CCT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CCT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CCT2 antibodies...
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CCT2 Infographic by Boster Bio
All CCT2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9992
100 μg/vial
Cat # PB9992
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, WB
$380
Cat # M05524-1
100ul
Cat # M05524-1
100ul
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M05524-2
100 μl/vial
Cat # M05524-2
100 μl/vial
CCT2 Overview
Facts about T-complex protein 1 subunit beta.
T-complex protein 1 subunit beta (CCT2)
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444).
As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Gene Information
| Human | |
|---|---|
| Gene Name: | CCT2 |
| Uniprot: | P78371 |
| Entrez: | 10576 |
Family
| Belongs to: |
|---|
| TCP-1 chaperonin family |
Alternative Names
Cctb; CCT-beta; CCTBPRO1633,99D8.1; chaperonin containing t-complex polypeptide 1, beta subunit; chaperonin containing t-complex polypeptide 1, subunit 2; chaperonin containing TCP1, subunit 2 (beta); MGC142074; MGC142076; T-complex protein 1 subunit beta; T-complex protein 1, beta subunit; TCP-1-beta
Molecular Weight
Mass (kDA):
57.488 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q15 |
| Sequence: | 12; NC_000012.12 (69585459..69601570) |
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Nervousness
- Liver Carcinoma
- Malignant Neoplasm Of Breast
- Diabetic Neuropathies
- Diabetes Mellitus, Non-insulin-dependent
- Liver Neoplasms
- Stomach Neoplasms
- Colonic Neoplasms
- Malignant Tumor Of Colon
Interacting Proteins
- BBS7
- CCT4
- CCT7
- SSSCA1
- TCP1
Pathways
- Translation
- Cell Cycle
- Cell Growth
- Regulation Of Cell Cycle
- Drug Resistance
- Ribosome Biogenesis
- Protein Folding
- Cold Acclimation
- Endoderm Development
- Cell Proliferation
- Cdp-choline Pathway
- Osteoblast Differentiation
- Dna Repair
PTMs
- Phosphorylation
Research Areas
- Cell Cycle and Replication
- Membrane Trafficking and Chaperones
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCT2
bosterbio.com/bosterbio-gene-info-cards/CCT2
References
PMID: 9819444 by Won K.-A., et al. Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT.
PMID: 14532270 by Imai Y., et al. A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.