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- Table of Contents
4 Citations 8 Q&As
12 Citations 7 Q&As
6 Citations 8 Q&As
1 Citations
Facts about C-C motif chemokine 3.
One of the Significant HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Human | |
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Gene Name: | CCL3 |
Uniprot: | P10147 |
Entrez: | 6348 |
Belongs to: |
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intercrine beta (chemokine CC) family |
C-C motif chemokine 3; MIP1-(a); AI323804; CCL3; chemokine (C-C motif) ligand 3; G0S19-1; LD78a; LD78alpha; MIP1 alpha; MIP-1 alpha; MIP1A; MIP-1alpha; MIP1-alpha; PAT 464.1; SCYA3; SIS-beta
Mass (kDA):
10.085 kDA
Human | |
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Location: | 17q12 |
Sequence: | 17; NC_000017.11 (36088256..36090143, complement) |
Secreted.
PMID: 3086300 by Obaru K., et al. A cDNA clone used to study mRNA inducible in human tonsillar lymphocytes by a tumor promoter.
PMID: 2521882 by Zipfel P.F., et al. Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors.
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