CCKAR Antibodies

AND CCKAR ELISA kits, CCKAR Proteins

Many biological assays use antibodies to detect CCKAR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CCKAR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CCKAR antibodies...

We validate the specificity of these antibodies to CCKAR by testing them on tissues known to express CCKAR positively and negatively. Browse below to find the CCKAR antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CCKAR Infographic by Boster Bio

All CCKAR Products

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Anti-CCK-AR Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A03985
100ul

CCKAR Overview

Facts about Cholecystokinin receptor type A.

CCKAR 3D structure. Source: alphafold

Cholecystokinin receptor type A (CCKAR)

Receptor for cholecystokinin.
Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach.

Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behaviour in the peripheral and central nervous system.

Gene Information

Human
Gene Name:	CCKAR
Uniprot:	P32238
Entrez:	886

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

CCK1R; CCK1-R; CCK-A R; CCK-A receptor; CCK-A; CCKAR; CCK-AR; CCKRA; cholecystokinin A receptor; cholecystokinin receptor type A; cholecystokinin type-A receptor; Cholecystokinin-1 receptor

Molecular Weight

Mass (kDA):
47.841 kDA

Genomic Context


Human

Location:	4p15.2
Sequence:	4; NC_000004.12 (26481396..26490484, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Obesity
Neoplasms
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Malignant Neoplasms
Hallucinations
Schizophrenia
Hyperinsulinism
Panic Disorder
Anxiety Disorders
Nervousness

Pancreatic Neoplasm
Hyperglycemia
Malignant Neoplasm Of Pancreas
Carcinoma
Delirium
Paranoid Schizophrenia

Pathways

Localization
Pathogenesis
Secretion
Glucose Homeostasis
Gastric Emptying
Receptor Internalization
Mating
Gene Silencing
Insulin Secretion
Aging
Dna Demethylation
Regulation Of Receptor Internalization
Endocytosis

Demethylation
Methylation
Regeneration
Gastric Motility
Maternal Behavior
Regulation Of Glucose Homeostasis
Feeding Behavior

PTMs

Demethylation

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCKAR

References

PMID: 8503909 by Ulrich C.D., et al. Molecular cloning and functional expression of the human gallbladder cholecystokinin A receptor.

PMID: 8343165 by Wank S.A., et al. Molecular cloning, functional expression and chromosomal localization of the human cholecystokinin type A receptor.