Chromobox protein homolog 8 (Cbx8)

Part of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class necessary to keep the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts through chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).

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