CBX1 Antibodies

AND CBX1 ELISA kits, CBX1 Proteins

Many biological assays use antibodies to detect CBX1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CBX1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CBX1 antibodies...

We validate the specificity of these antibodies to CBX1 by testing them on tissues known to express CBX1 positively and negatively. Browse below to find the CBX1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CBX1 Infographic by Boster Bio

All CBX1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Chromobox protein homolog 1 CBX1 Monoclonal Antibody

Human, Monkey

ELISA, Flow Cytometry, IF, WB

$380
Cat # M04206
100ul

Anti-HP beta CBX1 Monoclonal Antibody

Bovine, Canine, Chicken, Human, Mouse, Rat, Swine

$380
Cat # M04206-1
100ul

CBX1 (NM_006807) Human Recombinant Protein

$1062
Cat # PROTP83916
20 µg

Anti-CBX1/HP1 beta Antibody Picoband®

Human, Mouse, Rat

ELISA, IF, IHC, WB

$370
Cat # A04206-2
100 μg/vial

CBX1 (NM_006807) Human Over-expression Lysate

Human

$628
Cat # LS010951
100 µg

CBX1 Overview

Facts about Chromobox protein homolog 1.

CBX1 3D structure. Source: alphafold

Chromobox protein homolog 1 (CBX1)

Component of heterochromatin.
Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.

Interaction with lamin B receptor (LBR) can result in the association of the heterochromatin with the inner nuclear membrane. .

Gene Information

Human
Gene Name:	CBX1
Uniprot:	P83916
Entrez:	10951

Family

Belongs to:

No superfamily

Alternative Names

CBXM31HP1-BETA; chromobox homolog 1 (Drosophila HP1 beta); chromobox homolog 1 (HP1 beta homolog Drosophila ); chromobox homolog 1; chromobox protein homolog 1; Heterochromatin protein 1 homolog beta; heterochromatin protein 1-beta; heterochromatin protein p25 beta; Heterochromatin protein p25; HP1 beta homolog; HP1 beta; HP1Hsbeta; HP1Hs-beta; MOD1; Modifier 1 protein; p25beta

Molecular Weight

Mass (kDA):
21.418 kDA

Genomic Context


Human

Location:	17q21.32
Sequence:	17; NC_000017.11 (48070059..48101478, complement)

Tissue Specificity

Expressed in all adult and embryonic tissues.

Subcellular Localizations

Nucleus. Unassociated with chromosomes during mitosis.

Diseases

Malignant Neoplasms
Neoplasms
Neurofibromatosis 1
Fracture Of First Cervical Vertebra
Malignant Neoplasm Of Breast
Endometrial Neoplasms
Myeloid Leukemia, Chronic
Partial Deletion Of Y
Infertility
Edema
Steroid Sulfatase Deficiency Disease
Mammary Neoplasms

Lentivirus Infections
Invasive Malignant Neoplasm
Cell Invasion
Leukemogenesis
Cell Transformation, Neoplastic
Impacted Tooth

Interacting Proteins

ADNP
ADNP2
EMSY
HIST1H3A
NR2F6

SGO1
SUV39H1
ZNF280C

Pathways

Gene Silencing
Meiosis
Localization
Methylation
Metaphase
Fertilization
Cell Cycle
Interphase
Heterochromatin Organization
Regulation Of Gene Expression
Chromosome Segregation
Chromatin Organization
Chromosome Condensation

Male Meiosis
S Phase
Pachytene
Nuclear Envelope Reassembly
Transposition
Cell Migration
Cerebral Cortex Development

PTMs

Methylation

Phosphorylation

Cleavage

Research Areas

Chromatin Research

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CBX1

References

PMID: 9169582 by Furuta K., et al. Heterochromatin protein HP1Hsbeta (p25beta) and its localization with centromeres in mitosis.

PMID: 10460410 by Minc E., et al. Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells.