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- Table of Contents
Facts about Caveolae-associated protein 2.
Plays a role in caveola formation at a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia.
Human | |
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Gene Name: | CAVIN2 |
Uniprot: | O95810 |
Entrez: | 8436 |
Belongs to: |
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CAVIN family |
Caveolae-associated protein 2
Mass (kDA):
47.173 kDA
Human | |
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Location: | 2q32.3 |
Sequence: | 2; NC_000002.12 (191834310..191847088, complement) |
Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.
Cytoplasm, cytosol. Membrane, caveola. Localizes in the caveolae in a caveolin-dependent manner.
PMID: 10191091 by Gustincich S., et al. The human serum deprivation response gene (SDPR) maps to 2q32-q33 and codes for a phosphatidylserine-binding protein.
PMID: 2390065 by Burgener R., et al. Purification and characterization of a major phosphatidylserine- binding phosphoprotein from human platelets.