Caspase-5 Antibodies

AND CASP5 ELISA kits, Caspase-5 Proteins

Many biological assays use antibodies to detect Caspase-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-5 antibodies...

We validate the specificity of these antibodies to Caspase-5 by testing them on tissues known to express CASP5 positively and negatively. Browse below to find the CASP5 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CASP5 Infographic by Boster Bio

All CASP5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Caspase 5 CASP5 Rabbit Monoclonal Antibody

1 Q&As

Human

IP, IF, IHC, ICC, WB

$370
Cat # M05259
100 μl

Anti-Caspase-5 CASP5 Antibody

Human, Mouse

ELISA, IF, ICC, WB

$449
Cat # A05259-1
0.1 mg

Anti-Caspase 5 p10 CASP5 Antibody

Human, Mouse, Rat

$405
Cat # A05259-2
100ul

Anti-Caspase 5 CASP5 Antibody

Human

IP, IF, IHC, ICC, WB

$405
Cat # A05259-3
100ul

Anti-Cleaved-Caspase-5 p10 (S331) CASP5 Antibody

Human

ELISA, WB

$380
Cat # A05259S331
100ul

Anti-Caspase-5/CASP5 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05259-4
100 μg/vial

Caspase 5 (CASP5) (NM_004347) Human Over-expression Lysate

Human

$628
Cat # LS000838
100 µg

CASP5 Overview

Facts about Caspase-5.

CASP5 3D structure. Source: alphafold

Caspase-5 (CASP5)

Mediator of programmed cell death (apoptosis). Throughout non-canonical inflammasome activation, cuts CGAS and might play a role in the regulation of antiviral innate immune activation (PubMed:28314590).

Gene Information

Human
Gene Name:	CASP5
Uniprot:	P51878
Entrez:	838

Family

Belongs to:

peptidase C14A family

Alternative Names

CASP5; CASP-5; caspase 5, apoptosis-related cysteine peptidase; caspase 5, apoptosis-related cysteine protease; Caspase5; Caspase-5; EC 3.4.22; EC 3.4.22.58; ICE(rel)III; ICE(rel)-III; ICEREL-III; ICH3; ICH-3; MGC141966; Protease ICH-3; Protease TY; TY protease

Molecular Weight

Mass (kDA):
49.736 kDA

Genomic Context


Human

Location:	11q22.3
Sequence:	11; NC_000011.10 (104994235..105023902, complement)

Tissue Specificity

Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.

Diseases

Malignant Neoplasms
Neoplasms
Microsatellite Instability
Colorectal Cancer
Mutation, Out-of-frame
Carcinoma
Endometrial Polyp
Hereditary Nonpolyposis Colorectal Cancer
Cell Transformation, Neoplastic
Adenocarcinoma
Malignant Neoplasm Of Lung
Malignant Neoplasm Of Breast
Malignant Tumor Of Colon

Blind Vision
Colorectal Neoplasms
Carcinogenesis
Lung Neoplasms
Leukemia
Endometrial Carcinoma
Cholangiocarcinoma

Pathways

Mismatch Repair
Cell Death
Localization
Translation
Protein Folding
Immune Response
Pathogenesis
Chromosome Localization
Cell Proliferation
Mastication
Dna Repair
Donor Selection
Mitochondrial Depolarization

Inflammatory Response
Methylation
Innate Immune Response
Cell Growth
Angiogenesis
Segmentation
Apoptotic Process

PTMs

Cleavage
Phosphorylation

Dephosphorylation
Methylation

Research Areas

Apoptosis
Cancer
Caspases

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CASP5

References

PMID: 16893518 by Eckhart L., et al. Identification of a novel exon encoding the amino-terminus of the predominant caspase-5 variants.

PMID: 7797592 by Munday N.A., et al. Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases.